Table 2 ORs for In-hospital Mortality Associated with AC Placement for Sepsis with or without Shock Patients

Method	All patients with AC placement				Patients with AC placement within 24 h
	Septic shock		Sepsis without shock		Septic shock		Sepsis without shock
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
Propensity score matching	1.06 (0.84—1.35)	0.624	1.34 (1.17—1.54)	< 0.001	0.99 (0.78 – 1.27)	0.950	1.08 (0.93 – 1.27)	0.306
Propensity score IPTW	1.05 (0.86 -1.28)	0.654	1.33 (1.18—1.50)	< 0.001	0.97 (0.79 – 1.20)	0.805	1.15 (1.00 – 1.31)	0.044
Multivariable logistic regression	0.99 (0.78—1.26)	0.960	1.37 (1.20—1.57)	< 0.001	0.93 (0.74 – 1.16)	0.518	1.14 (0.99 – 1.31)	0.061

Multivariable logistic regression was adjusted for age, gender, weight, admission type, ethnicity, first care unit, SOFA score, SAPII, Charlson Comorbidity Index, CHF, renal disease, COPD, malignancy, liver disease, heart rate, temperature, MAP, WBC count, hemoglobin, hematocrit, platelet, sodium, potassium, bicarbonate, chloride, BUN, creatine, glucose, anion gap, INR, PT, APTT, receipt of CRRT, MV, and sedative medication. IPTW, inverse probability of treatment weighting. P < 0.0013 were considered statistically significant

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