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Table 1 Characteristics of included trials comparing US-PNBs to systemic analgesia

From: Ultrasound-guided peripheral nerve blocks for preoperative pain management in hip fractures: a systematic review

   

Intervention

Control

Author (year)

N

Site

Type of PNB

LA type and dose

Time from admission to surgery

Analgesic treatment

Sham-

block

Time from admission to surgery

Beaudoin [15] (2013)

36

USA

US-guided single shot FNB

25 ml 0.5% bupivacaine

480 (324-670) min (median, range)

iv. morphine

3 ml saline sc.

510 (341-704) min (median, range)

Beaupre [16] (2020)

73

Canada

US-guided single shot FNB

10 ml 1% ropivacaine + 5 ml 0.25% bupivacaine

29.8 (14.3) hours

Unspecified standard care treatment

None

26.8 (12.3) hours

Diakomi [17] (2020)

198

Greece

US-guided single shot FICB

40 ml 0.5% ropivacaine

No data

iv. 0.5 µg.kg-1 fentanyl as rescue

2 ml saline in inguinal region

No data

Dickman [18] (2010)

64

USA

US-guided single shot FNB

or

US-guided single shot FICB

30 ml 0.25% bupivacaine

No data

One dose of iv. 0.1 mg.kg-1 morphine sulphate

None

No data

Hao [19] (2019)

90

China

US-guided continuous FICB

30 ml 0.45% ropivacaine

29.49 (4.58) hours

0.05 mg im. fentanyl at VAS ≥ 5

Sham catheter (continuous saline infusion)

29.81 (3.78) hours

Jang [20] (2018)

34

South Korea

US-guided single shot FNB

0.3 ml.kg-1 up to 20 ml 0.5% bupivacaine

Elective surgery after 48 hours

iv. tramadol

3 ml saline sc.

Elective surgery after 48 hours

Luger [21] (2012)

20

Austria

US-guided continuous FNB

30 ml 0.25% bupivacaine

26.8 (18.6) hours

iv. piritramide and PCM

None

24.9 (1.7) hours

Ma [22] (2018)

88

China

US-guided continuous FICB

50 ml 0.4% ropivacaine

3.27 (0.82) days

po. tramadol and PCM

None

3.34 (0.89) days

Morrison [23] (2016)

161

USA

US-guided single shot FNB

20 ml 0.5% bupivacaine

1.5 (0-4) days (mean, range)

po. and iv. standard care (opioids and PCM)

None

1.4 (0-7) days (mean, range)

Thompson [27] (2020)

47

USA

US-guided single shot FICB

30 ml 0.25% ropivacaine

No data

PCM, tramadol or morphine according to VAS

None

No data

Uysal [28] (2020)

110

Turkey

Dual-guided continuous FNB

10 ml 0.25% bupivacaine

No data

iv. 15 mg.kg-1 PCM, 0.5 mg.kg-1 tramadol as rescue

None

No data

Yamamoto [29] (2019)

53

Japan

US-guided single shot FICB

40 ml 0.25% levobupivacaine

No data

iv. 1000 mg PCM at 6 and 12 hours post-op

None

No data

  1. Data is presented as mean (SD) unless else is stated
  2. N number of randomised participants, PNB peripheral nerve block, US-guided ultrasound-guided, FNB femoral nerve block, FICB fascia iliaca compartment block, LA local anaesthetic, PCM paracetamol, iv. intravenous, sc. subcutaneous, im. intramuscular, po. peroral, VAS visual analogue scale, post-op postoperatively