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Table 2 Duration of analgesia (min), duration of sensory blockade (min) and duration of motor blockade (min)

From: Dexmedetomidine prolongs the duration of local anesthetics when used as an adjuvant through both perineural and systemic mechanisms: a prospective randomized double-blinded trial

End point

Control group

DexP group

DexIV group

P

post hoc analyses

Duration of analgesia (min)

633 ± 127

997 ± 243

654 ± 159

 < 0.001

A, C

Duration of sensory blockade (min)

 musculocutaneous nerve

168 ± 18

197 ± 44

205 ± 57

0.025

A, B

 posterior brachial cutaneous nerve

166 ± 17

199 ± 41

196 ± 51

0.015

A, B

 median nerve

633 ± 127

997 ± 244

649 ± 164

 < 0.001

A, C

 ulnar nerve

626 ± 122

996 ± 242

654 ± 159

 < 0.001

A, C

 radial nerve

633 ± 136

994 ± 243

642 ± 162

 < 0.001

A, C

Duration of motor blockade (min)

 elbow

167 ± 17

193 ± 43

194 ± 42

0.034

A, B

 wrist

171 ± 17

196 ± 41

196 ± 42

0.047

A, B

  1. Data are presented as mean ± SD, n = 20 for all groups. P < 0.05 considered statistically significant. A: DexP group differs from Control group (P < 0.05). B: DexIV group differs from Control group (P < 0.05). C: DexP group differs from DexIV group (P < 0.05)
  2. Duration of analgesia: Control group vs. DexP group, P < 0.001; Control group vs. DexIV group, P = 0.792; DexP group vs. DexIV group, P < 0.001
  3. Duration of sensory blockade of musculocutaneous nerve (min): Control group vs. DexP group, P = 0.039; Control group vs. DexIV group, P = 0.010; DexP group vs. DexIV group, P = 0.586
  4. Duration of sensory blockade of posterior brachial cutaneous nerve (min): Control group vs. DexP group, P = 0.008; Control group vs. DexIV group, P = 0.018; DexP group vs. DexIV group, P = 0.755
  5. Duration of sensory blockade of median nerve (min): Control group vs. DexP group, P < 0.001; Control group vs. DexIV group, P = 0.792; DexP group vs. DexIV group, P < 0.001
  6. Duration of sensory blockade of ulnar nerve (min): Control group vs. DexP group, P < 0.001; Control group vs. DexIV group, P = 0.628; DexP group vs. DexIV group, P < 0.001
  7. Duration of sensory blockade of radial nerve (min): Control group vs. DexP group, P < 0.001; Control group vs. DexIV group, P = 0.874; DexP group vs. DexIV group, P < 0.001
  8. Duration of motor block of elbow (min): Control group vs. DexP group, P = 0.026; Control group vs. DexIV group, P = 0.022; DexP group vs. DexIV group, P = 0.941
  9. Duration of motor block of wrist (min): Control group vs. DexP group, P = 0.033; Control group vs. DexIV group, P = 0.030; DexP group vs. DexIV group, P = 0.915
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BMC Anesthesiology

ISSN: 1471-2253

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