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Table 4 Comparison of sedation-related side effects between the two groups (N = 77)

From: Remimazolam tosilate compared with propofol for gastrointestinal endoscopy in elderly patients: a prospective, randomized and controlled study

 

RT group (N = 39)

Propofol group (N = 38)

P value

Injection pain (N.)

0*

5

0.025

Haemodynamics

 Preoperation

  Baseline MAP (mmHg)

79.0 ± 4.4

79.5 ± 4.2

0.652

  Baseline HR (bpm)

65.5 ± 4.2

67.0 ± 4.1

0.118

 One minute after induction

  MAP (mmHg)

72.1 ± 4.9*

68.0 ± 4.1

< 0.001

  HR (bpm)

58.6 ± 3.8*

56.3 ± 3.9

0.026

Haemodynamic events (N.)

6*

17

0.005

Respiratory depression (N.)

2*

9

0.026

PONV (N.)

10

8

0.419

Dizziness/headache (N.)

11

14

0.286

  1. Data are expressed as the frequencies or means ± SDs, as appropriate
  2. MAP Mean arterial pressure, HR Heart rate, PONV Postoperative nausea and vomiting
  3. * P<0.05 compared to the Propofol group
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BMC Anesthesiology

ISSN: 1471-2253

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