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Table 3 Baseline demographic data of study population group by AKI

From: Correlation between perioperative parecoxib use and postoperative acute kidney injury in patients undergoing radical mastectomy: a retrospective cohort analysis

Clinical features

Without AKI(n = 3338)

With AKI(n = 204)

P

Age (years)

45.29 ± 9.56

45.06 ± 9.59

0.63

BMI

22.64 ± 6.22

22.18 ± 3.46

0.15

eGFR

100.28 ± 18.88

77.61 ± 37.41

 < 0.001

Alcohol consumption

40 (1.20%)

2 (0.98%)

0.78

Anemia

649 (19.44%)

58 (28.43%)

0.002

Hypertension

705 (21.12%)

66 (32.35%)

 < 0.001

Diabetes mellitus

166 (4.97%)

17 (8.33%)

0.03

ACEI

58 (1.74%)

4 (1.96%)

0.81

ARB

33 (0.99%)

3 (1.47%)

0.50

CCB

417 (12.44%)

37 (18.14%)

0.02

Diuretics

33 (0.99%)

6 (2.94%)

0.01

ASA grade

  

 < 0.001

 I–II

2704 (81.01%)

144 (70.59%)

 

 III–V

634 (18.99%)

60 (29.41%)

 

Operative time (min)

  

0.004

  ≤ 60

446 (13.36%)

23 (11.27%)

 

 61–120

882 (26.42%)

34 (16.67%)

 

 121–180

852 (25.52%)

58 (28.43%)

 

  > 180

1158 (34.69%)

89 (43.63%)

 

Intraoperative erythrocyte Transfusion, mL (%)

  

0.004

  < 100

2596 (77.77%)

137 (67.16%)

 

 100–600

353 (10.58%)

31 (15.20%)

 

 601–1000

181 (5.42%)

14 (6.86%)

 

  > 1000

208 (6.23%)

22 (10.78%)

 

Intraoperative Hemorrhage, mL (%)

  

0.12

  < 100

1054 (31. 58%)

57 (27.94%)

 

 100–600

1824 (54.64%)

109 (53.43%)

 

 601–1000

240 (7.19%)

22 (10.78%)

 

  > 1000

220 (6.59%)

16 (7.84%)

 

In fluid amount (10 mL/24 h)

937.50 (625.00–1375.00)

1135.42 (729.17–1526.04)

 < 0.001

Out fluids amount (10 mL/24 h)

312.50(145.83–541.67)

333.33 (187.50–625.00)

0.02

Intraoperative hypotension

363(10.87%)

29(14.21%)

0.005

Parecoxib

332 (9.95%)

12 (5.88%)

0.05

Admission to ICU

90 (2.70%)

8 (3.92%)

0.30

Death

7 (0.21%)

4 (1.96%)

 < 0.001

  1. AKI Acute Kidney Injury, BMI Body Mass Index, eGFR estimated Glomerular Filtration Rate, ACEI Angiotensin-converting Enzyme Inhibitors, ARB Angiotensin Receptor Blockers, CCB Calcium-channel Blockers, ASA American Society of Anesthesiologists, Intraoperative hypotension: MAP < 60 mmHg, ICU Intensive Care Unit. Data are expressed as number of patients (%) or Mean ± SD