Variables | RA + GA (n = 266) | GA (n = 936) | adj P-value for site clusters |
---|---|---|---|
Preoperative Peripheral Saturation of Oxyhemoglobin (SpO2), % | 97.7 (2.0) | 97.1 (2.2) | < 0.0001 |
Procedure Characteristics | |||
 Emergency Surgery | 4 (1.5) | 57 (6.1) | 0.0472 |
 Abdominal/Pelvic Surgery | 174 (65.4) | 371 (39.6) | 0.0003 |
 Surgery Duration, hours | 3.9 (2.1) | 3.6 (2.0) | 0.1034 |
 Anesthesia Duration, hours | 4.8 (2.2) | 4.6 (2.2) | 0.3486 |
Mechanical ventilation | |||
 Ventilatory Modes |  |  | 0.4295 |
 Volume Controlled Ventilation | 187 (70.3) | 637 (68.1) |  |
 Pressure Controlled Ventilation | 47 (17.7) | 131 (14.0) |  |
 Assisted/Supported Ventilation | 7 (2.6) | 41 (4.4) |  |
 Unspecified | 25 (9.4) | 126 (13.5) |  |
 Median Exhaled Tidal Volume (VT), mL/kgPBW | 8.0 (1.4) | 8.0 (1.7) | 0.1543 |
 Median Inspired Fraction of Oxygen (FiO2), % | 53.9 (12.1) | 54.6 (14.3) | 0.4305 |
 Median End-Expiratory Pressure (PEEP), cmH2O | 5 (1) | 5 (2) | 0.9420 |
 Median Peak Inspiratory Pressure, cmH2O | 20.7 (4.9) | 21.4 (5.5) | 0.0218 |
Fluid Balance | |||
 Estimated Blood Loss, mL | 456.8 (948) | 310.5 (531) | 0.0106 |
 Urine Output, mL/kg/h | 1.11 (1.26) | 1.28 (1.61) | 0.0750 |
 Crystalloids (ml/kg/hr) | 6.97 (3.89) | 6.14 (3.59) | 0.0027 |
 Colloids (mL/kg/hr) | 0.5 (1.2) | 0.3 (0.7) | <.0001 |
 Any Blood Product transfused | 33 (12.4) | 99 (10.6) | 0.4243 |
Neuromuscular Blockade and Reversal Management | |||
 Depolarizing neuromuscular blockade | 97 (36.6) | 343 (36.7) | 0.9697 |
 Non-Depolarizing neuromuscular blockade | 245 (92.1) | 793 (84.8) | 0.0223 |
 Neuromuscular blockade monitoring | 194 (80.5) | 555 (68.4) | 0.0116 |
 Neostigmine Dose, mcg/kg | 37.1 (24.3) | 29.9 (23.8) | < 0.0001 |
Hypnotics and Analgesics Administered (Any Dose) | |||
 Propofol | 98 (36.8) | 413 (44.2) | 0.0392 |
 Fentanyl | 257 (96.6) | 857 (91.6) | 0.0331 |
 Hydromorphone | 126 (47.4) | 509 (54.4) | 0.0222 |
 Morphine | 8 (3.0) | 61 (6.5) | 0.0942 |
 Remifentanil | 34 (12.8) | 176 (18.8) | 0.0064 |
 Ketamine | 24 (9.0) | 135 (14.4) | 0.1382 |