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Table 2 Perioperative characteristics

From: Postoperative pulmonary complications with adjuvant regional anesthesia versus general anesthesia alone: a sub-analysis of the Perioperative Research Network study

Variables

RA + GA (n = 266)

GA (n = 936)

adj P-value for site clusters

Preoperative Peripheral Saturation of Oxyhemoglobin (SpO2), %

97.7 (2.0)

97.1 (2.2)

< 0.0001

Procedure Characteristics

 Emergency Surgery

4 (1.5)

57 (6.1)

0.0472

 Abdominal/Pelvic Surgery

174 (65.4)

371 (39.6)

0.0003

 Surgery Duration, hours

3.9 (2.1)

3.6 (2.0)

0.1034

 Anesthesia Duration, hours

4.8 (2.2)

4.6 (2.2)

0.3486

Mechanical ventilation

 Ventilatory Modes

  

0.4295

 Volume Controlled Ventilation

187 (70.3)

637 (68.1)

 

 Pressure Controlled Ventilation

47 (17.7)

131 (14.0)

 

 Assisted/Supported Ventilation

7 (2.6)

41 (4.4)

 

 Unspecified

25 (9.4)

126 (13.5)

 

 Median Exhaled Tidal Volume (VT), mL/kgPBW

8.0 (1.4)

8.0 (1.7)

0.1543

 Median Inspired Fraction of Oxygen (FiO2), %

53.9 (12.1)

54.6 (14.3)

0.4305

 Median End-Expiratory Pressure (PEEP), cmH2O

5 (1)

5 (2)

0.9420

 Median Peak Inspiratory Pressure, cmH2O

20.7 (4.9)

21.4 (5.5)

0.0218

Fluid Balance

 Estimated Blood Loss, mL

456.8 (948)

310.5 (531)

0.0106

 Urine Output, mL/kg/h

1.11 (1.26)

1.28 (1.61)

0.0750

 Crystalloids (ml/kg/hr)

6.97 (3.89)

6.14 (3.59)

0.0027

 Colloids (mL/kg/hr)

0.5 (1.2)

0.3 (0.7)

<.0001

 Any Blood Product transfused

33 (12.4)

99 (10.6)

0.4243

Neuromuscular Blockade and Reversal Management

 Depolarizing neuromuscular blockade

97 (36.6)

343 (36.7)

0.9697

 Non-Depolarizing neuromuscular blockade

245 (92.1)

793 (84.8)

0.0223

 Neuromuscular blockade monitoring

194 (80.5)

555 (68.4)

0.0116

 Neostigmine Dose, mcg/kg

37.1 (24.3)

29.9 (23.8)

< 0.0001

Hypnotics and Analgesics Administered (Any Dose)

 Propofol

98 (36.8)

413 (44.2)

0.0392

 Fentanyl

257 (96.6)

857 (91.6)

0.0331

 Hydromorphone

126 (47.4)

509 (54.4)

0.0222

 Morphine

8 (3.0)

61 (6.5)

0.0942

 Remifentanil

34 (12.8)

176 (18.8)

0.0064

 Ketamine

24 (9.0)

135 (14.4)

0.1382

  1. (Data are presented as average (SD) or number (% of respective column), as appropriate)