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Table 3 Evolution of hemodynamic Variables in fluid responders and nonresponders at baseline or after fluid challenge

From: Efficacy of using tidal volume challenge to improve the reliability of pulse pressure variation reduced in low tidal volume ventilated critically ill patients with decreased respiratory system compliance

 

non responder (n = 45)

responder (n = 31)

Baseline 1

After Vt Challenge

Baseline 2

After Fluid Challenge

Baseline 1

After Vt Challenge

Baseline 2

After Fluid Challenge

Vt, 6 mL/kg

Vt, 8 mL/kg

Vt, 6 mL/kg

Vt, 6 mL/kg

Vt, 6 mL/kg

Vt, 8 mL/kg

Vt, 6 mL/kg

Vt, 6 mL/kg

Heart Rate

110 ± 18

109 ± 18

109 ± 18

107 ± 17

116 ± 14

116 ± 14

116 ± 14

112 ± 14

MAP (mm Hg)

75 ± 16

76 ± 14

77 ± 14

76 ± 15

78 ± 16

74 ± 18

74 ± 18

82 ± 15

CCI (L/min/m2)

2.88 ± 0.58

2.80 ± 0.77

2.81 ± 0.60

2.95 ± 0.62

3.14 ± 0.40a

3.20 ± 0.56a

3.18 ± 0.32a

3.71 ± 0.44ac

CVP (mm Hg)

9.8 ± 2.0

11.1 ± 2.3

10.0 ± 2.1

13.3 ± 3.4c

8.6 ± 2.5a

9.9 ± 2.4a

8.5 ± 2.6a

10.4 ± 2.5ac

PPV (%)

6.8 ± 3.1

8.5 ± 3.0b

6.7 ± 3.5

5.4 ± 4.6

8.8 ± 2.7a

13.0 ± 1.7ab

8.7 ± 3.2a

6.2 ± 3.8c

CVP6-8

 

1.5 ± 1.3

   

1.4 ± 1.1

  

PPV6-8

 

1.7 ± 1.1

   

4.2 ± 1.6a

  

Driving pressure (cm H2O)

15 ± 1.9

20 ± 2.2b

–

–

15 ± 2.0

20 ± 2.5b

–

–

Cst (mL.cm H2O−1)

26.1 ± 3.7

26.3 ± 3.3

–

–

25.1 ± 3.9

25.2 ± 3.6

–

–

CITPTD (L.min−1.m−2)

2.89 ± 0.58

–

–

2.93 ± 0.57

3.16 ± 0.36a

–

–

3.74 ± 0.37ad

GEDVI (mL.m−2)

810 ± 88

–

–

806 ± 136

743 ± 119a

–

–

752 ± 120

  1. Vt tidal volume, MAP Mean arterial pressure, CCI Continuous cardiac index which was provided by pulse contour analysis, CITPTD Cardiac index assessed by transpulmonary thermodilution, Cst static compliance of the respiratory system, GEDVI Global end-diastolic volume index
  2. Values are expressed as mean ± sd
  3. ap < 0.05, fluid responders vs fluid nonresponders
  4. bp < 0.05, Vt 8 mL/kg vs baseline 1 (Vt = 6 ml/kg)
  5. cp < 0.05, baseline 2 vs after fluid bolus
  6. dp < 0.05, baseline 1 (Vt, 6 mL/kg) vs after fluid bolus (Vt, 6 mL/kg PBW)
  7. Dashes indicate variables that were not measured in monitoring CITPTD and GEDVI
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BMC Anesthesiology

ISSN: 1471-2253

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