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Table 2 Baseline Hemodynamic and Respiratory Characteristics of Fluid Responders and Nonresponders

From: Efficacy of using tidal volume challenge to improve the reliability of pulse pressure variation reduced in low tidal volume ventilated critically ill patients with decreased respiratory system compliance

Parameters

Overall population (n = 76)

Fluid non-responders (n = 45)

Fluid responders (n = 31)

p

Norepinephrine dose (μg.kg−1.min−1)

0.55 ± 0.39

0.61 ± 0.41

0.45 ± 0.35

0.08

Heart rate (min−1)

112 ± 16

110 ± 18

116 ± 14

0.06

MAP (mm Hg)

76 ± 16

75 ± 16

78 ± 16

0.39

PPV (%)a

7.6 ± 3.1

6.7 ± 3.1

8.8 ± 2.7

0.004

CVP (mm Hg)

9.3 ± 2.3

9.8 ± 2.0

8.6 ± 2.5

0.025

CITPTD (L.min−1.m−2)

2.98 ± 0.53

2.88 ± 0.58

3.14 ± 0.40

0.003

GEDVI (ml.m−2)

783 ± 106

810 ± 88

743 ± 118

0.007

Respiratory rate (min−1)

27 ± 4

27 ± 4

27 ± 4

.807

Tidal volume (ml.kg−1 PBW)

6.0

6.0

6.0

.401

PEEP (cm H2O)

9.5 ± 2.8

9.9 ± 3.0

8.8 ± 2.4

.082

Pplat (cm H2O)

23 ± 3.3

23.1 ± 3.3

22.7 ± 3.4

.587

Driving pressure (cm H2O)

15 ± 2.0

15 ± 1.9

15 ± 2.0

.770

Cst (mL.cm H2O−1)

25.7 ± 3.8

26.1 ± 3.7

25.1 ± 3.9

.811

PaO2/FiO2 (mm Hg)

199 ± 71

193 ± 70

208 ± 73

.349

Arterial lactate (mmol.L−1)

3.8 ± 2.0

4.0 ± 2.1

3.4 ± 1.8

.193

  1. Data are presented as mean ± SD or median (1st quartile to 3rd quartile)
  2. P values were calculated between the fluid non-responders and fluid responders
  3. MAP Mean arterial pressure, PPV Pulse pressure variation, CVP Central venous pressure, CITPTD Cardiac index assessed by transpulmonary thermodilution, GEDVI Global end-diastolic volume index, PBW Predicted body weight, PEEP Positive end-expiratory pressure, Pplat Plateau pressure of the respiratory system, Cst Static compliance of the respiratory system, PaO2 Partial pressure of arterial oxygen, FiO2 Inspired oxygen fraction