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Table 3 Univariable and multivariable analysis of factors associated with PPCs after cytoreduction surgery for ovarian cancer patients

From: Postoperative pulmonary complications and outcomes in cytoreductive surgery for ovarian cancer: a propensity-matched analysis

 

Univariate analysis

Multivariate analysis

OR (95%CI)

P value

OR (95%CI)

P value

Age (Y)

0.99 (0.97–1.03)

0.948

  

BMI (kg m−2)

0.99 (0.91–1.08)

0.849

  

ASA grade

1.77 (0.87–3.59)

0.116

  

Preoperative comorbidities

 Hypertension

1.52 (0.77–2.99)

0.224

  

 Diabetes

0.96 (0.36–2.53)

0.930

  

 Preoperative DVT

1.09 (0.33–3.61)

0.882

  

 Preoperative albumin (g L−1)

0.92 (0.87–0.98)

0.006

  

 Preoperative hemoglobin (g L−1)

1.01 (0.99–1.02)

0.588

  

Pulmonary function

 FEV1 (L)

1.97 (0.51–7.63)

0.328

  

 Neo-adjuvant chemotherapy

0.49 (0.16–1.48)

0.206

  

 Intraoperative fluid infusion volume (L)

1.79 (1.39–2.29)

< 0.001

1.34 (1.01–1.77)

0.040

 Blood transfusion volume (L)

1.89 (1.32–2.70)

0.001

  

 Blood loss volume (L)

1.47 (1.14–1.89)

0.003

  

 Operation time (h)

1.81 (1.48–2.20)

< 0.001

  

Diaphragmatic surgery

 

< 0.001

  

 Electrocoagulation/cauterization

2.68 (0.85–8.45)

0.093

  

 DP/stripping

5.22 (2.32–11.75)

< 0.001

  

 DFTR with direct closure

12.20 (4.37–34.09)

< 0.001

  

 DFTR with patch

30.50 (11.27–82.57)

< 0.001

  

 Diameter size of diaphragmatic resection (cm)

1.31 (1.19–1.44)

< 0.001

1.16 (1.06–1.28)

0.002

 SCS

1.42 (1.29–1.57)

< 0.001

1.26 (1.13–1.42)

<  0.001

 FIGO stage

3.29 (1.96–5.51)

< 0.001

  

 Anesthesia means

1.43 (0.72–2.84)

0.304

  

 Postoperative albumin (g L− 1)

0.89 (0.84–0.94)

< 0.001

  
  1. PPCs Postoperative pulmonary complications, OR Odds ratio, CI Confidence intervals, BMI Body mass index, ASA American Society of Anesthesiologists, DVT Deep vein thrombosis, COPD Chronic obstructive pulmonary disease, FEV1 Forced expiratory volume in 1 s, DP diaphragm peritonectomy, DFTR diaphragm full-thickness resection, SCS Surgical complexity scores, FIGO Federation International of Gynecology and Obstetrics, GA general anesthesia, TAP block transversus abdominis plane block