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Table 1 Clinical characteristics of ovarian cancer patients

From: Postoperative pulmonary complications and outcomes in cytoreductive surgery for ovarian cancer: a propensity-matched analysis

Clinical Characteristics

PPCs Group

Non-PPCs Group

P value

Number

72 (26.9%)

196 (73.1%)

 

Age (Y)a

55.0 ± 8.6

55.1 ± 10.7

0.035

BMI (kg/m2)a

23.0 ± 3.2

23.1 ± 3.1

0.954

ASA grade

  

0.268

 II

1 (1.4%)

4 (2.0%)

 

 III

58 (80.6%)

171 (87.2%)

 

 IV

13 (18.1%)

21 (10.7%)

 

Preoperative comorbidities

 Hypertension

16 (22.2%)

31 (15.8%)

0.222

 Diabetes

6 (8.3%)

17 (8.7%)

0.930

 Heart disease

0 (0.0%)

7 (3.6%)

0.195

 Preoperative DVT

4 (5.6%)

10 (5.1%)

0.547

 COPD

2(2.8%)

2 (1.0%)

0.293

 Obsolete pulmonary tuberculosis

0 (0.0%)

1 (0.5%)

0.731

 Smoking history

1 (1.4%)

1 (0.5%)

0.466

Pulmonary function (L)b

 FEV1

2.27 (2.15–2.37)

2.25 (2.15–2.35)

0.415

 Neo-adjuvant chemotherapy

4 (5.6%)

21 (10.7%)

0.206

 Preoperative hemoglobin (g/L)a

116.9 ± 12.9

115.7 ± 16.1

0.041

 Preoperative albumin (g/L)a

39.8 ± 4.6

41.6 ± 4.7

0.693

 Intraoperative fluid infusion volume (L)b

3.5 (3.0–4.0)

2.5 (2.0–3.5)

< 0.001

 Blood transfusion volume (L)b

0.8 (0.6–1.6)

0.6 (0.0–0.8)

< 0.001

 Blood loss volume (L)b

1.0 (0.8–1.6)

0.8 (0.4–1.0)

< 0.001

 Operation time (h)a

5.8 ± 1.8

4.2 ± 1.5

0.164

Surgery methods

  

0.059

 Primary cytoreductive surgery

61 (84.7%)

139 (70.9%)

 

 Intermediate cytoreductive surgery

3 (4.2%)

22 (11.2%)

 

 Re-cytoreductive surgery

8 (11.1%)

35 (17.9%)

 

Diaphragmatic surgery

  

< 0.001

 No diaphragmatic lesions

12 (16.7%)

122 (62.2%)

 

 Electrocoagulation/cauterization

5 (6.9%)

19 (9.7%)

 

 DP/stripping

19 (26.4%)

37 (18.9%)

 

 DFTR with direct closure

12 (16.7%)

10 (5.1%)

 

 DFTR with patch

24 (33.3%)

8 (4.1%)

 

 Maximum diameter size of diaphragmatic resection (cm)b

0.5 (0.0–8.0)

0.0 (0.0–0.0)

< 0.001

 SCSb

9 (6–13)

5 (4–7)

< 0.001

Residual disease

  

< 0.001

 0

60 (83.3%)

174 (88.8%)

 

  < 1 cm

12 (16.7%)

22 (11.2%)

 

FIGO stage

  

< 0.001

 I

1 (1.4%)

16 (8.2%)

 

 II

1 (1.4%)

40 (20.4%)

 

 III

53 (73.6%)

122 (62.2%)

 

 IV

17 (23.6%)

18 (9.2%)

 

Anesthesia means

  

0.302

 GA

13 (18.1%)

47 (24%)

 

 GA combined with TAP block

59 (81.9%)

149 (76%)

 

 Postoperative albumin (g/L)a

29.0 ± 5.0

32.0 ± 4.8

0.632

 Admission to ICU after operation

19 (26.4%)

21 (10.7%)

0.001

Hospitalization characteristics

   

 ICU length of stay (d)b

0.0 (0.0–1.0)

0.0 (0.0–0.0)

0.002

 Length of stay (d)b

26.0 (19.0–34.5)

17.5 (14.0–23.0)

< 0.001

Outcomes

   

 Mortality, in-hospital

2 (2.8%)

0 (0.0%)

0.071

 Readmission, 30d

8 (11.1%)

5 (2.6%)

0.008

  1. PPCs Postoperative pulmonary complications, BMI Body mass index, ASA American Society of Anesthesiologists, DVT Deep vein thrombosis, COPD Chronic obstructive pulmonary disease, FEV1 forced expiratory volume in 1 s, DP diaphragm peritonectomy, DFTR diaphragm full-thickness resection, SCS Surgical complexity scores, FIGO Federation International of Gynecology and Obstetrics, GA general anesthesia, TAP block transversus abdominis plane block
  2. aData are presented as mean ± standard deviation (SD)
  3. bData are presented as median, interquartile range (IQR)