Table 3 Prediction of fluid responsiveness using the receiver operating characteristic curves and gray zones of IVC related parameters and CVP under two respiratory modes
Respiratory mode | Parameters | AUROC curve (95% CI) | p-value | Optimal cut-off value | Sensitivity (%)(95% CI) | Specificity (%)(95% CI) | Youden index | Gray zones | Patients in gray zones (%) |
|---|---|---|---|---|---|---|---|---|---|
Mechanical ventilation | cIVC1 * | 0.80 (0.68–0.90) | < 0.0001 | > 15.32 | 100 (89–100) | 65 (43–84) | 0.65 | 17.01–25.93 | 44.6 |
ΔIVC * | 0.80 (0.67–0.90) | < 0.0001 | > 0.29 | 85 (68–95) | 65 (43–84) | 0.50 | 0.27–0.36 | 48.2 | |
IVCmax | 0.65 (0.51–0.77) | > 0.05 | ≤ 1.69 | 67 (48–82) | 61 (39–80) | 0.28 | 1.32–1.96 | 60.7 | |
IVCmin | 0.73 (0.60–0.84) | 0.002 | ≤ 1.44 | 88 (72–97) | 57 (35–77) | 0.44 | 0.99–1.54 | 57.1 | |
CVP | 0.57 (0.43–0.70) | > 0.05 | ≤ 1 | 24 (11–42) | 96 (78–100) | 0.20 | 2.04–9.69 | 76.8 | |
Spontaneous breathing | cIVC2 *,† | 0.87 (0.75–0.94) | < 0.0001 | > 30.25 | 91 (71–99) | 71 (53–85) | 0.62 | 30.72–38.32 | 23.2 |
ΔIVC | 0.76 (0.62–0.86) | < 0.001 | > 0.46 | 86 (65–97) | 62 (44–78) | 0.48 | 0.41–0.61 | 51.8 | |
IVCmax | 0.77 (0.64–0.87) | < 0.0001 | ≤ 1.53 | 73 (50–89) | 71 (53–85) | 0.43 | 1.29–1.87 | 51.8 | |
IVCmin * | 0.85 (0.73–0.93) | < 0.0001 | ≤ 1.14 | 86 (65–97) | 71 (53–85) | 0.57 | 0.82–1.19 | 30.4 | |
CVP | 0.64 (0.50–0.76) | > 0.05 | ≤ 4 | 82 (60–95) | 47 (30–65) | 0.29 | 0–4.9 | 64.3 |