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Table 4 Association of circadian variation of heart rate with Mortality in different SOFA score subgroups

From: Association between circadian variation of heart rate and mortality among critically ill patients: a retrospective cohort study

 

ICU mortality

Hospital mortality

30-day mortality

1-year mortality

SOFA score (0–5)

OR (95%CI)

OR (95%CI)

HR (95% CI)

HR (95% CI)

 Model 1

1.180(0.703–1.980)

1.175(0.784–1.761)

1.078(0.782–1.484)

1.099(0.884–1.366)

 Model 2

1.157(0.688–1.947)

1.155(0.769–1.735)

1.056(0.767–1.455)

1.086(0.874–1.350)

 Model 3

1.385(0.794–2.416)

1.295(0.841–1.992)

1.113(0.806–1.538)

1.096(0.880–1.364)

 Model 4

1.385(0.791–2.425)

1.280(0.830–1.975)

1.100(0.796–1.521)

1.086(0.872–1.353)

 Model 5

1.482(0.813–2.642)

1.345(0.860–2.104)

1.108(0.799–1.535)

1.062(0.852–1.325)

 Model 6

1.416(0.792–2.534)

1.304(0.833–2.043)

1.099(0.793–1.525)

1.049(0.840–1.308)

 Model 7

1.534(0.848–2.777)

1.359(0.863–2.138)

1.162(0.836–1.617)

1.053(0.844–1.315)

SOFA score (6–24)

OR (95% CI)

OR (95% CI)

HR (95% CI)

HR (95% CI)

 Model 1

1.493(1.171–1.903)

1.481(1.185–1.851)

1.436(1.181–1.745)

1.301(1.104–1.533)

 Model 2

1.492(1.168–1.906)

1.483(1.184–1.857)

1.434(1.180–1.743)

1.306(1.108–1.539)

 Model 3

1.480(1.134–1.932)

1.487(1.163–1.901)

1.414(1.160–1.722)

1.318(1.117–1.557)

 Model 4

1.445(1.104–1.889)

1.453(1.135–1.861)

1.390(1.141–1.695)

1.296(1.097–1.531)

 Model 5

1.453(1.091–1.935)

1.457(1.122–1.891)

1.380(1.132–1.682)

1.289(1.091–1.522)

 Model 6

1.453(1.091–1.936)

1.457(1.122–1.891)

1.355(1.111–1.652)

1.274(1.078–1.504)

 Model 7

1.444(1.084–1.924)

1.442(1.110–1.873)

1.331(1.091–1.624)

1.263(1.069–1.493)

  1. Model 1 unadjusted
  2. Model 2 adjusted for age, gender, and ethnicity
  3. Model 3 adjusted for Model 2 plus Respiratory failure, Renal failure, Liver cirrhosis, Shock, Diabetes uncomplicated, Diabetes complicated, AIDS, Lymphoma, Metastatic cancer, Coagulopathy, Rheumatoid arthritis, Infection, Poisoning, and Hypoferric anemia
  4. Model 4 adjusted for Model 3 plus Medication taking in day 1 (including sedatives, catecholamine, β-blockers, Opioid analgesics)
  5. Model 5 adjusted for Model 4 plus Sequential Organ Failure Assessment, and Simplified Acute Physiology Score-I
  6. Model 6 adjusted for Model 5 plus length of stay in ICU
  7. Model 7 adjusted for Model 6 plus average heart rate in the first 24 h