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Table 3 Association of circadian variation of heart rate with Mortality in Overall Patients

From: Association between circadian variation of heart rate and mortality among critically ill patients: a retrospective cohort study

Logistic Regression

ICU mortality

Hospital mortality

OR

95% CI

P

OR

95% CI

P

Model 1

1.471

1.218–1.775

 < 0.001

1.471

1.218–1.775

 < 0.001

Model 2

1.463

1.210–1.768

 < 0.001

1.463

1.210–1.768

 < 0.001

Model 3

1.470

1.192–1.813

 < 0.001

1.470

1.192–1.813

 < 0.001

Model 4

1.417

1.146–1.752

0.001

1.417

1.146–1.752

0.001

Model 5

1.398

1.116–1.750

0.003

1.398

1.116–1.750

0.003

Model 6

1.397

1.115–1.748

0.004

1.397

1.115–1.748

0.004

Model 7

1.393

1.112–1.745

0.004

1.393

1.112–1.745

0.004

Cox

Regression

30-day mortality

1-year mortality

HR

95% CI

P

HR

95% CI

P

Model 1

1.387

1.175–1.638

 < 0.001

1.261

1.107–1.438

 < 0.001

Model 2

1.376

1.165–1.624

 < 0.001

1.254

1.100–1.429

0.001

Model 3

1.341

1.135–1.586

0.001

1.253

1.098–1.430

0.001

Model 4

1.307

1.105–1.546

0.002

1.233

1.081–1.408

0.002

Model 5

1.294

1.094–1.531

0.003

1.218

1.067–1.390

0.003

Model 6

1.277

1.079–1.510

0.004

1.212

1.062–1.383

0.004

Model 7

1.260

1.064–1.491

0.007

1.207

1.057–1.378

0.005

  1. Model 1 unadjusted
  2. Model 2 adjusted for age, gender, and ethnicity
  3. Model 3 adjusted for Model 2 plus Respiratory failure, Renal failure, Liver cirrhosis, Shock, Diabetes uncomplicated, Diabetes complicated, AIDS, Lymphoma, Metastatic cancer, Coagulopathy, Rheumatoid arthritis, Infection, Poisoning, and Hypoferric anemia
  4. Model 4 adjusted for Model 3 plus Medication taking in day 1 (including sedatives, catecholamine, β-blockers, Opioid analgesics)
  5. Model 5 adjusted for Model 4 plus Sequential Organ Failure Assessment, and Simplified Acute Physiology Score-I
  6. Model 6 adjusted for Model 5 plus length of stay in ICU
  7. Model 7 adjusted for Model 6 plus average heart rate in the first 24 h