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Table 2 Adverse events and interruptions during the procedure

From: Comparison of propofol-nalbuphine and propofol-fentanyl sedation for patients undergoing endoscopic retrograde cholangiopancreatography: a double-blind, randomized controlled trial

 

GroupPF(N = 199)

GroupPN(N = 201)

p value

95% CI

Odds ratio

Respiratory depression(n)% a

24 (12.06%)

12 (5.97%)

 < 0.0001

1.04–3.93

2.16

subclinical respiratory a depression(n)% a

10 (5.03%)

6 (2.99%)

0.14

0.86–1.88

1.72

hypoxia(n)% a

14 (7.04%)

6 (2.99%)

0.03

1.06–1.95

2.46

minor risk hypoxia(n)% a

9(4.52%)

5(2.49%)

0.13

0.87–1.96

1.86

severe risk hypoxia(n)% a

5(2.51%)

1(0.50%)

0.048

1.17–2.45

1.69

18-65y Age-related Respiratory depression(n)% a

15(11.36%)

7(5.26%)

 < 0.0001

1.04–1.94

2.31

66-80y Age-related Respiratory depression(n)% a

9(13.43%)

5(7.35%)

 < 0.0001

0.87–2.07

1.96

Correction of hypoxia(n)% a

24 (12.06%)

12 (5.97%)

 < 0.0001

1.04–3.93

2.16

Method I(n)% a

12 (6.03%)

8 (3.98%)

0.24

0.84–1.77

1.55

Methods I + II(n)% a

4 (2.01%)

1 (0.50%)

0.09

1.03–2.54

1.62

Methods I + II + III(n)% a

6 (3.02%)

3 (1.49%)

0.15

0.84–2.17

2.05

Methods I + II + III + IV(n)% a

2 (1.01%)

0 (0.00%)

0.07

1.83–2.23

2.02

Surgical interruptions(n)% a

45 (22.61%)

30 (14.93%)

0.02

1.02–1.57

1.27

The score for patient movement(points)b

9.61 ± 1.01

9.59 ± 1.07

0.37

-0.23–0.25

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  1. Values are presented as the frequency (%),Chi-squared testa.Values are presented as the mean ± SD, one-sample t test b. Methods: (I) opening the airway with the jaw-thrust manoeuvre; (II) placing the nasopharyngeal airway; (III) turningthe patients over to the supine position; and (IV) tracheal intubation for mechanical ventilation