Table 3 Subgroup Analysis of the Comorbidities between serum Chloride at 72 h after ICU Admission and 30 day All-cause Mortality
N | No Hyperchloremia (Cl72h < 108) HR (95% CI) | Hyperchloremia (Cl72h ≥ 108) HR (95% CI) | P value | P for interaction | |
|---|---|---|---|---|---|
Coronary heart disease | 0.418 | ||||
No | 1885 | 1.0 (ref) | 1.69 (1.26 ~ 2.25) | < 0.001 | |
Yes | 246 | 1.0 (ref) | 2.17 (1.05 ~ 4.51) | 0.037 | |
Hypertension | 0.157 | ||||
No | 1149 | 1.0 (ref) | 1.3 (0.89 ~ 1.9) | 0.169 | |
Yes | 982 | 1.0 (ref) | 2.36 (1.61 ~ 3.48) | < 0.001 | |
Diabetes mellitus | 0.103 | ||||
No | 1587 | 1.0 (ref) | 1.93 (1.43 ~ 2.62) | < 0.001 | |
Yes | 544 | 1.0 (ref) | 1.25 (0.69 ~ 2.27) | 0.465 | |
Acute kidney injury | 0.017 | ||||
No | 1623 | 1.0 (ref) | 2.22 (1.57 ~ 3.14) | < 0.001 | |
Yes | 508 | 1.0 (ref) | 1.06 (0.68 ~ 1.66) | 0.794 |