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Table 2 Hazard ratios and 95% confidence intervals for mortality across groups of serum chloride at 72 h after ICU admission

From: Association of hyperchloremia with all-cause mortality in patients admitted to the surgical intensive care unit: a retrospective cohort study

Chloride

Non-adjusted

Model I

Model II

HR (95% CI)

P-value

HR (95% CI)

P-value

HR (95% CI)

P-value

Hospital all-cause mortality

 fitted groups, mmol/L

   < 108

1.0 (ref)

 

1.0 (ref)

 

1.0 (ref)

 

   ≥ 108

1.47 (1.15, 1.87)

0.002

1.32 (1.04 ~ 1.69)

0.025

1.35 (1.02 ~ 1.77)

0.035

30-day all-cause mortality

 fitted groups, mmol/L

   < 108

1.0 (ref)

 

1.0 (ref)

 

1.0 (ref)

 

   ≥ 108

1.86 (1.47, 2.35)

< 0.001

1.68 (1.32 ~ 2.12)

< 0.001

1.67 (1.28 ~ 2.19)

< 0.001

90-day all-cause mortality

 fitted groups, mmol/L

   < 108

1.0 (ref)

 

1.0 (ref)

 

1.0 (ref)

 

   ≥ 108

1.64 (1.35, 1.98)

< 0.001

1.51 (1.24 ~ 1.83)

< 0.001

1.39 (1.12 ~ 1.73)

0.003

  1. Models were derived using Cox proportional hazards regression models
  2. Non-adjusted model adjusted for: none
  3. Adjust I model adjust for: age, ethnicity, male
  4. Adjust II model adjust for: age, ethnicity, male, SAPS II, RRT, Cl0, Scr72h, bicarbonate72h, PLT72h
  5. HR hazard ratio, CI confidence interval, SAPS II Simplified Acute Physiology Score II, RRT renal replacement therapy, Cl0 admission serum chloride, Scr72h creatinine72h, PLT72h platelet72h