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Table 4 Multivariate logistic regression analysis of factors independently associated with hospital mortality

From: Gender- and age-based differences in outcomes of mechanically ventilated ICU patients: a Chinese multicentre retrospective study

Variables

All patients (n = 853)

< 65 years (n = 328)

≥ 65 years (n = 525)

AOR (95% CI)

P value

AOR (95% CI)

P value

AOR (95% CI)

P value

Age (years)

1.026 (1.014–1.039)

< 0.001

1.013 (0.986–1.040)

0.356

1.062 (1.030–1.096)

< 0.001

Male gender

1.611 (1.101–2.356)

0.014

0.879 (0.446–1.731)

0.709

2.074 (1.315–3.269)

0.002

ICU admission source: Medical ward

1.650 (1.092–2.493)

0.018

2.330 (0.993–5.464)

0.052

1.393 (0.864–2.245)

0.174

APACHE II scores

1.079 (1.055–1.105)

< 0.001

1.080 (1.038–1.124)

< 0.001

1.096 (1.066–1.127)

< 0.001

Hospital LOS (days)

0.984 (0.977–0.992)

< 0.001

0.995 (0.982–1.008)

0.446

0.986 (0.978–0.994)

< 0.001

Events occurring over the course of MV

 Barotrauma a

10.613 (2.942–38.285)

< 0.001

14.561 (2.619–80.957)

0.002

9.075 (1.530–53.820)

0.015

 VAP

1.763 (1.103–2.819)

0.018

2.199 (0.916–5.281)

0.078

2.004 (1.182–3.397)

0.010

 Reintubation

2.271 (1.028–5.021)

0.043

1.974 (0.396–9.849)

0.407

2.541 (1.052–6.133)

0.038

 PMV b

1.869 (1.047–3.335)

0.034

2.543 (0.974–6.640)

0.057

1.493 (0.754–2.956)

0.250

Withhold/withdraw life sustaining treatments

10.928 (6.629–18.016)

< 0.001

17.021 (7.617–38.037)

< 0.001

9.715 (5.212–18.109)

< 0.001

  1. AOR adjusted odds ratio, CI confidence interval, ICU intensive care unit, APACHE II Acute Physiology and Chronic Health Evaluation II, LOS length of stay, MV mechanical ventilation, VAP ventilator-associated pneumonia, PMV prolonged mechanical ventilation
  2. a Barotrauma refers to the development of at least one of the following: interstitial emphysema, pneumothorax, pneumomediastinum, pneumoperitoneum or subcutaneous emphysema
  3. b PMV was defined as the need for mechanical ventilation for more than 21 days