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Table 1 The basic characteristics of the included studies

From: Unfractionated heparin improves the clinical efficacy in adult sepsis patients: a systematic review and meta-analysis

Article, year Number of researches centers Total (n),
UFH/Control
Population Age (Yr) P value
UFH Control
Deng et al, 2017 [22] 1 118,
62/56
Sepsis and septic shock 62.5 ± 13.9 61.5 ± 15.2 P > 0.05
Gu et al, 2014 [23] 1 42,
21/21
Sever sepsis 64.6 ± 12.7 69.7 ± 16.3 P > 0.05
Guo et al, 2019 [24] 1 90,45/45 Sepsis with pre-DIC 64.75 ± 7.88 68.87 ± 6.16 P > 0.05
Hou et al, 2011 [25] 1 40,
20/20
Sever sepsis 58.6 ± 15.4 57.7 ± 12.6 P > 0.05
Jaimes et al, 2009 [26] 1 319,
159/160
Sepsis 57 (IQR: 39–70) 55 (IQR: 40–72) P > 0.05
Levi et al, 2007 [27] 224 1440,
485/955
Sever sepsis 59.6 ± 16.1 58.4 ± 16.0 P = 0.90 > 0.05
Liu et al, 2014 [28] 1 37,
22/15
Sepsis 48.86 ± 14.3 47.47 ± 14.68 P = 0.935 > 0.05
Liu et al, 2009 [29] 1 27,
12/15
Sepsis 47.4 ± 16.8 48.3 ± 14.1 P = 0.708 > 0.05
Peng et al, 2013 [30] 1 112,
56/56
Sepsis with pre-DIC 63.5 ± 7.8 63.5 ± 7.8 P > 0.05
Wang et al, 2012 [31] 1 48,
24/24
Sepsis 52.7 ± 9.4 54.3 ± 8.6 P > 0.05
Wu et al, 2011 [32] 1 85,
45/40
Sepsis 68 ± 13 67 ± 14 P = 0.684 > 0.05
Zhang et al, 2006 [33] 1 22,
11/11
Sever sepsis 59.55 ± 6.15 59.36 ± 8.05 P > 0.05
Zhao et al, 2009 [34] 1 79,
37/42
Sepsis 61.5 ± 11.9 60.6 ± 15.9 P > 0.05
Zhao et al, 2007 [35] 1 52,
27/25
Sever sepsis NR NR P > 0.05
Zhang et al, 2016 [36] 1 106,
53/53
Sepsis 43.5 ± 6.6 43.5 ± 6.6 P > 0.05
  1. NR not reported, UFH unfractionated heparin, IQR interquartile range