Table 2 Perioperative clinical data
Clinical Data | L-MAP Group (n = 20) | H-MAP Group (n = 20) | P Value |
|---|---|---|---|
Hemodynamics parameter | |||
HR (bpm) | |||
baseline | 79 [72, 86] | 81 [75, 85] | 0.321 |
30 min post CPB | 88 [78, 92] | 87 [83, 90] | 0.827 |
at the end of the operation | 90 [83, 97] | 87 [80, 98] | 0.147 |
MAP (mmHg) | |||
before induction | 87 [73, 98] | 92 [83, 110] | 0.698 |
30 min post CPB | 67 [60, 70] | 70 [68, 73] | 0.697 |
end of the operation | 67 [63, 77] | 70 [63, 73] | 0.638 |
1 h after the operation | 68 [60,76] | 71 [68, 77] | 0.072 |
6 h after the operation | 71 [70, 79] | 68 [64, 72] | 0.543 |
24 h after the operation | 75 [70, 79] | 70 [61, 75] | 0.646 |
Perioperative medications | |||
Anesthetics | |||
Propofol (mg) | 2683.2 [2080,2878.4] | 2142.4 [1820, 2534.4] | 0.457 |
Sufentanil (μg) | 56.2 [48, 63.4] | 52.8 [49.4, 63.4] | 0.607 |
Midazolam (mg) | 8.4 [7.2, 9.5] | 7.9 [7.4, 9.5] | 0.521 |
Cis-atracurium (mg) | 67.1 [52, 72] | 58.6 [45.5, 79.1] | 0.472 |
Remifentanil (μg) | 33.5 [26, 36] | 29.3 [22.8, 39.6] | 0.416 |
Vasopressor drugs | |||
Phenylephrine during CPB (mg) | 0.35 [0.15, 0.48] | 0.4 [0.3, 0.52] | 0.854 |
Norepinephrine during CPB (mg) | 0.17 [0, 0.19] | 0.72 [0.47, 0.95] | 0.000*** |
Epinephrine within 24 h after the operation (mg) | 0.72 [0, 1.8] | 0 [0, 0] | 0.024* |
Dopamine within 24 h after the operation (mg) | 314 [0, 420] | 0 [0, 300] | 0.088 |
Vasodilator drugs | |||
Nitroglycerin during CPB (mg) | 1.4 [0, 2.1] | 0 [0, 2.2] | 0.000*** |
Nitroglycerin within 24 h after the operation (mg) | 0 [0, 0.5] | 0 [0, 0.7] | 0.243 |
Laboratory parameters | |||
HCT (%) | |||
during CPB | 26.8 [24.2, 29.8] | 25.9 [25.2, 28.8] | 0.892 |
at end of surgery | 29.8 [29.2, 34.8] | 28.9 [28.7, 33.8] | 0.317 |
Blood glucose during CPB (mM•L−1) | 8.4 [7.3, 9.6] | 8.6 [6.9, 9.2] | 0.874 |
Cr (ųM•L−1) | |||
Baseline | 78 [63, 90] | 74 [60, 84] | 0.558 |
6 h after the operation | 72 [58.8, 88] | 79 [52, 93] | 0.690 |
24 h after the operation | 75 [57, 91] | 75 [63, 86] | 0.706 |
BUN (mM•L−1) | |||
Baseline | 6.6 [5.3, 7.1] | 6.0 [5.0, 6.8] | 0.774 |
6 h after the operation | 6.9 [5.1, 7.8] | 6.3 [5.2, 7.4] | 0.928 |
24 h after the operation | 7.9 [6.4, 9.8] | 7.5 [5.1, 9.8] | 0.935 |
Urine volume (ml) | |||
during CPB | 300 [200, 600] | 600 [300, 800] | 0.086 |
24 h after the operation | 2855 [2700, 3130] | 3010 [2410, 3330] | 0.589 |
Outcome data | |||
Extubation time (h) | 17 [17,18] | 11 [6,16] | 0.042* |
Length of stay in the ICU (h) | 43 [42, 68] | 36 [19, 43] | 0.008** |
Readmission within 30 days (n) | 0 | 0 | null |
Mortality in 1 year (%) | 0 | 0 | null |