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Fig. 8 | BMC Anesthesiology

Fig. 8

From: Circ_MUC16 attenuates the effects of Propofol to promote the aggressive behaviors of ovarian cancer by mediating the miR-1182/S100B signaling pathway

Fig. 8

Propofol blocked A2780 and SK-OV-3 cell malignant behaviors by sequestering S100B. A The protein level of S100B in different doses of Propofol-treated A2780 and SK-OV-3 cells was checked by western blot. B The efficiency of S100B overexpression was checked by western blot. Then, in Propofol-treated A2780 and SK-OV-3 cells transfected with S100B or pcDNA, C the protein level of S100B was checked by western blot. D Cell viability was detected by MTT assay. E Colony formation ability was detected using colony formation assay. F-H Glucose consumption, lactate production and ATP level were investigated using matched kits. I-K Cell migration was assessed by transwell assay and wound healing assay, and cell invasion was assessed by transwell assay. **P < 0.01 and ***P < 0.001

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