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Fig. 6 | BMC Anesthesiology

Fig. 6

From: Circ_MUC16 attenuates the effects of Propofol to promote the aggressive behaviors of ovarian cancer by mediating the miR-1182/S100B signaling pathway

Fig. 6

Propofol blocked A2780 and SK-OV-3 cell malignant behaviors by enriching miR-1182. A The expression of miR-1182 in different doses of Propofol-treated A2780 and SK-OV-3 cells was checked by qPCR. B The efficiency of miR-1182 inhibitor was checked by qPCR. Then, in Propofol-treated A2780 and SK-OV-3 cells transfected with anti-miR-1182 or anti-miR-NC, C the expression of miR-1182 was checked by qPCR. D Cell viability was checked by MTT assay. E Colony formation ability was checked by colony formation assay. F-H Glycolysis consumption, lactate production and ATP level were measured using matched kits. I-K Cell migration and invasion were assessed by transwell assay, and cell migration was also assessed by wound healing assay. *P < 0.05, **P < 0.01 and ***P < 0.001

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BMC Anesthesiology

ISSN: 1471-2253

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