Association between enterocyte injury and fluid balance in patients with septic shock: a post hoc exploratory analysis of a prospective observational study

Table 1 Baseline characteristics of patients with septic shock

Characteristics	Median (IQR)
Age, years	71 (62–79)
Male, n (%)	35 (61)
Body mass index, kg/m²	22 (19–24)
APACHE II score	30 (25–36)
SOFA score	13 (11–15)
JAAM DIC score	5 (3–7)
Baseline data and setting at ICU admission
Mean arterial pressure, mmHg	81 (73–90)
Heart rate, beats/min	103 (92–113)
Central venous pressure, mmHg	11 (9–14)
Inotropic score ^a	40 (25–55)
PaO₂/F_IO₂ ratio	227 (174–290)
PEEP, cmH₂O	8 (5–8)
Peak inspiratory pressure, cmH₂O	21 (20–23)
pH	7.29 (7.26–7.34)
HCO₃⁻, mmol/L	17.7 (15.5–20.2)
Lactate, mmol/L	3.0 (2.1–6.8)
Procalcitonin, ng/mL	42.5 (10.7–118.2)
NT-proBNP, ng/mL	9585 (2388–24,389)
eGFR, mL/min/1.73 m^{2 b}	20 (11–38)
Intervention after ICU admission
Vasopressin, n (%)	28 (49)
Steroid, n (%)	46 (81)
Continuous renal replacement therapy, n (%)	46 (81)
Polymyxin B-direct hemoperfusion, n (%)	31 (54)

Abbreviations: APACHE Acute Physiology and Chronic Health Evaluation, DIC Disseminated intravascular coagulation, eGFR Estimated glomerular filtration rate, ICU Intensive care unit, IQR Interquartile range, JAAM Japanese Association for Acute Care Medicine, NT-proBNP N-terminal pro-B-type natriuretic peptide, PEEP Positive end-expiratory pressure, SOFA Sequential Organ Failure Assessment
Data are reported as median (IQR), unless otherwise indicated
^a Inotropic score calculated as (dopamine dose × 1) + (dobutamine dose × 1) + (epinephrine dose × 100) + (norepinephrine dose × 100), where all doses are expressed in micrograms per kilogram per minute
^b eGFR calculated as 194 × Cr (mg/dL)^-1.094 × age^-0.287 (if female, × 0.739)

ISSN: 1471-2253