Fig. 3

Effects of fentanyl, sufentanil, and remifentanil on U937-HUVEC adhesion. a Effects on U937-HUVEC adhesion when U937 monocytes are pre-treated with fentanyl, sufentanil, and remifentanil (n = 6, *P < 0.05 vs control). U937-HUVECs adhesion is detected by adhesion assays. The data of adhesion fraction are normalized to control. b Effects on U937-HUVEC adhesion when HUVECs are pre-treated with fentanyl, sufentanil, and remifentanil (n = 6, *P < 0.05 vs control). U937-HUVECs adhesion is detected by adhesion assays. The data of adhesion fraction are normalized to control. Fentanyl (Fen): 10 μg/ml, for 24 h; sufentanil (Suf): 25 ng/ml, for 24 h; remifentanil (Remi): 50 ng/ml, for 24 h. HUVEC, human umbilical vein endothelial cell. All experiments are conducted in the presence of TNF-α. All data are presented as mean ± S.D.. Multiple comparisons among groups are performed using repeated-measures one-way analyses of variance, followed by Tukey post hoc comparisons