Table 3 A review of currently used drugs for aspiration prophylaxis
S.No | Drugs Used for Aspiration Prophylaxis | Current recommendations |
|---|---|---|
1 | Gastrointestinal Stimulants (Metoclopramide) | • Admnistering preoperative gastrointestinal Stimulants might be used for patients at increased risk of pulmonary aspiration. • Routine administration of preoperative gastrointestinal stimulants for the purpose of reducing the risk of pulmonary aspiration in patients with no apparent increased risk for pulmonary aspiration is not recommended. |
2 | Gastric Acid Secretion blockers (Proton pump inhibitor: omeprazole, pantoprazole; Histamine-2 receptor antagonists: cimetidine, ranitidine;) | • Administering drugs that block gastric acid secretion preoperatively may be used in patients at increased risk of pulmonary aspiration. • Routine administration of preoperative gastric acid secretion blockers for the purpose of reducing the risk of pulmonary aspiration in patients with no apparent increased risk for pulmonary aspiration is not recommended. |
3 | Antacids (sodium citrate) | • Administering nonparticulate antacids preoperatively may be used in patients at increased risk of pulmonary aspiration. • Routine administration of preoperative non-particulate antacids to reduce the risk of pulmonary aspiration in patients with no apparent increased risk for pulmonary aspiration is not recommended. |