Variable | Non-intubated within 24 h (N = 707) | Intubated within 24 h (N = 345) | P Value | ||
---|---|---|---|---|---|
Age (y) | 69.5 | (59.4, 80.2) | 66.0 | (55.4, 74.2) | < 0.001 |
Sex | Â | Â | Â | Â | 0.24 |
 Male | 383 | (54) | 200 | (58) |  |
  Female | 324 | (32) | 145 | (33) |  |
BMI (kg/m2), n = 701/339 | 28.2 | (23.6, 34.5) | 28.5 | (24.5, 35.1) | 0.18 |
ICU admission source | Â | Â | Â | Â | 0.007 |
  Emergency Department | 328 | (32) | 134 | (34) |  |
  Direct admit (from an outside facility) | 249 | (35) | 156 | (36) |  |
  Transfer from the floor | 130 | (18) | 55 | (16) |  |
APACHE III score | 68 | (57, 82) | 92 | (74, 115) | < 0.001 |
SOFA score (day 1) | 6 | (4,8) | 10 | (8,13) | < 0.001 |
SOFA score (day 2), n = 589/334 | 4 | (2,7) | 7 | (4,10) | < 0.001 |
Failed to resolve within 6 h per MAP | 113 | (16) | 30 | (9) | 0.001 |
Failed to resolve within 6 h per lactate | 230 | (37) | 137 | (38) | 0.022 |
Non-invasive ventilation use | 108 | (15) | 62 | (18) | 0.26 |
Days on invasive ventilation, n = 153/345 | 0.8 | (0.3, 2.0) | 2.3 | (1.1, 4.8) | < 0.001 |
ICU mortality | 37 | (5) | 59 | (17) | < 0.001 |
ICU length of stay (d), n = 670/286 | 2.0 | (1.3, 3.1) | 3.7 | (2.3, 6.9) | < 0.001 |
Hospital mortality | 82 | (12) | 89 | (26) | < 0.001 |
Hospital length of stay (d), n = 625/256 | 6.8 | (4.5, 11.4) | 10.3 | (6.6, 20.6) | < 0.001 |