Comparison of the resonance sonorheometry based Quantra® system with rotational thromboelastometry ROTEM® sigma in cardiac surgery – a prospective observational study

Table 1 Comparison between Parameters output by the Quantra and the ROTEM sigma

Quantra	Units	Reagents	Reference Range	ROTEMsigma	Units	Reagents	Reference Range
CT	sec	kaolin	113–164 s	INTEM-CT	sec	ellagic acid	138–174 s
CTH	sec	kaolin + heparinase 1	109–150 s	HEPTEM-CT	sec	ellagic acid + heparinase 1	45–173 s
CS	hPa	thromboplastin + hexadimethrine bromide	13.0–33.2 hPa	EXTEM A10	hPa	tissue factor	3.5–8.2 hPa (41–62 mm)
FCS	hPa	Thromboplastin + hexadimethrine bromide + abciximab	1.0–3.7 hpa	FIBTEM A10	hPa	Tissue factor + cytochalasin D	0.3–1.6 hPa (5–24 mm)
PCS	hPa	Subtracting FCS from CS	11.9–29.8 hPa	EXTEM A10-FIBTEM A10	hPa	Subtracting FIBTEM A10 from EXTEM A10	3.2–6.2 hPa (36–38 mm)
CTR	Unitless	Ratio of CT over CTH	N/A		Unitless		N/A

ROTEM amplitudes (mm) were converted to shear modulus (hPa) by the formula G (hPa) = (5 x A)/(100-A), as described by Solomon et al.
Abbreviations: CT Coagulation time of the intrinsic coagulation pathway in seconds, CTH Clot time in the presence of heparinase in seconds, CS Clot stiffness in hPa, FCS Fibrinogen contribution to the clot stiffness in hPa, PCS Platelet contribution to clot stiffness in hPa, CTR Clot time ratio of CT and CT unitless, INTEM-CT Clot time in seconds (time from start the test until a clot firmness of 2 mm is detected), HEPTEM-CT Clot time of INTEM added with heparinase in seconds, EXTEM A10 Clot strength at 10 min after CT of the tissue factor activated test in hPa, FIBTEM A10 Clot strength at 10 min after CT of the tissue factor activated test added with cytochalasin in hPa, EXTEM A10 FIBTEM A10, platelet contribution to clot stiffness in hPa, hPa HectoPascal

ISSN: 1471-2253