| Univariable analysis a |  | Multivariable analysis b |  |
---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
Age, year | 0.97 (0.95, 1.00) | 0.069 | – | – |
Male sex | 0.43 (0.20, 0.92) | 0.029 | 0.27 (0.10, 0.71) | 0.008 |
ASA class (III + IV vs. I + II) |  |  | – | – |
 I + II | Ref |  | – | – |
 III + IV | 1.94 (0.94, 4.02) | 0.075 | – | – |
Mayo classification | ||||
 I + II | Ref |  | Ref | – |
 III + IV | 8.18 (3.18, 21.1) | < 0.001 | 4.21 (1.42, 12.4) | 0.009 |
Use of nitrous oxide during anesthesia | 0.46 (0.22, 0.95) | 0.037 | – | – |
Acute normovolemic hemodilution before surgery | 2.21 (1.09, 4.48) | 0.028 | 2.66 (1.10, 6.41) | 0.029 |
Duration of intraoperative hypotension, 20 min | 1.37 (1.11, 1.69) | 0.004 | – | – |
Duration of intraoperative tachycardia, 20 min | 1.73 (1.18, 2.53) | < 0.001 | 1.49 (1.03, 2.16) | 0.036 |
Intraoperative bradycardia | 2.99 (1.26, 7.06) | 0.013 | – | – |
Intraoperative allogeneic blood transfusion | 5.25 (2.40,11.49) | < 0.001 | – | – |
Complete IVC clamping during surgery | 3.62 (1.17, 11.26) | 0.026 | – | – |
Duration of surgery, h | 1.71 (1.37, 2.12) | < 0.001 | 1.48 (1.03, 2.16) | 0.009 |
Use of NSAIDs during perioperative period | 0.19 (0.09, 0.42) | < 0.001 | – | – |