Fig. 4
Effect of intravenous anesthetic on respiratory responses in vivo. A Time-course study of 1 median effective dose (ED50) and 2 ED50 propofol on respiratory frequency (Ai), tidal volume (Aii), and minute ventilation (Aiii) with 100% oxygen in vivo. B Scatterplot of 1 ED50 and 2 ED50 propofol on respiratory frequency (Bi), tidal volume (Bii), and minute ventilation (Biii) versus airflow (ml/sec) for each breath (dot) taken during the 30-min recording. C Time-course study of 1 ED50 and 2 ED50 etomidate on respiratory frequency (Ci), tidal volume (Cii), and minute ventilation (Ciii) with 100% oxygen in vivo. D Scatterplot of 1 ED50 and 2 ED50 etomidate on respiratory frequency (Di), tidal volume (Dii), and minute ventilation (Diii) versus airflow (ml/sec) for each breath (dot) taken during the 30-min recording. Data are expressed as mean ± standard deviation