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Fig. 4 | BMC Anesthesiology

Fig. 4

From: Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study

Fig. 4

Concentration–response curves for SRBAs. Concentration–response curves for CMGCD and sugammadex for reversing (A) pipecuronium-induced, (B) rocuronium-induced, (C) and vecuronium-induced neuromuscular block. Normalized contraction force amplitude as a function of SRBA concentration on a logarithmic scale (logarithm to base 10/ log10). The curve is the best fit curve calculated from measurements on n = 5 different specimens by non-linear regression. Measurement points represent mean values of normalized contraction force amplitude at a given concentration. Error bars show the standard deviation of measurement points. CMGCD: carboxymethyl-γ-cyclodextrin; SRBA: selective relaxant binding agent

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