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Fig. 2 | BMC Anesthesiology

Fig. 2

From: Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study

Fig. 2

Study design. A Concentration–response curves for NMBAs. A bolus of NMBA was given every 15 min until the suppression of ST response was achieved. B Concentration–response curves for SRBAs. After an initial bolus of NMBA to achieve 90–95% depression of ST force amplitude, SRBA boluses were given every 15 min until full reversal of neuromuscular block was achieved. A reversal dose of sugammadex was given after reversal with C to verify full reversal. NMBA: neuromuscular blocking agent; ST: single twitch; SRBA: selective relaxant binding agent; Pip: pipecuronium; Roc: rocuronium; Vec: vecuronium; Sug: sugammadex; C: carboxymethyl-γ-cyclodextrin

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BMC Anesthesiology

ISSN: 1471-2253

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