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Table 1 Demographic and perioperative characteristics

From: Effectiveness of analgesia with hydromorphone hydrochloride for postoperative pain following surgical repair of structural congenital malformations in children: a randomized controlled trial

Variable

Group

 

S

N = 74

H1

N = 74

H2

N = 74

P value (K-W Test)

Age (month); mean ± SD

14.93 ± 9.39

18.95 ± 12.79

15.19 ± 8.70

0.277

Gender (male)

50(67.57%)

46(62.16%)

51 (68.92%)

0.655

Weight (kg); mean ± SD

9.35 ± 2.15

10.33 ± 3.03

9.97 ± 2.38

0.096

ASA (II)a

74(100%)

74(100%)

74(100%)

1

Surgery

   

0.980 (Chi Square Test)

  Urinary system malformation repair

25(33.78%)

25(33.78%)

26(35.14%)

  Cleft lip, cleft palate or both repair

49(66.22%)

49(66.22%)

48(64.86%)

Administration of drug during the operation

  Propofol (mg); mean ± SD

30.54 ± 8.82

32.84 ± 7.77

30.86 ± 9.80

0.059

  Sulfentanil (mcg); mean ± SD

3.47 ± 0.94

3.73 ± 0.99

3.50 ± 1.20

0.116

  Cisatracurium (mg); mean ± SD

2.64 ± 0.72

2.51 ± 0.97

2.54 ± 1.06

0.733

  Tropisetron (mg); mean ± SD

1.11 ± 0.86

1.07 ± 0.28

1.00 ± 0.200

0.272

  Penehyclidine hydrochloride (mg); mean ± SD

0.05 ± 0.09

0.04 ± 0.05

0.04 ± 0.05

0.926

  Flurbiprofen axetil (mg); mean ± SD

10.01 ± 2.06

10.51 ± 2.89

10.00 ± 1.76

0.239

  Duration of surgery (min); mean ± SD

78.23 ± 45.79

67.07 ± 33.20

85.58 ± 55.09

0.126

  Duration of anesthesia (min); mean ± SD

107.70 ± 50.19

100.22 ± 41.05

104.84 ± 59.48

0.694

  Recovery time (min); mean ± SD

17.70 ± 5.82

16.28 ± 5.25

18.14 ± 5.62

0.033

  Length of hospital (day); mean ± SD

5.39 ± 3.33

5.14 ± 2.10

5.39 ± 3.27

0.812

  Cost of hospital (thousand Yuan); mean ± SD

16.76 ± 7.78

14.79 ± 4.03

16.38 ± 6.87

0.680

  1. aASA American Society of Anesthesiologists. Patients were randomized 1:1:1 into 3 groups: hydromorphone hydrochloride 0.1 mg/kg (H1), hydromorphone hydrochloride 0.2 mg/kg (H2), or sufentanil 1.5 µg/kg (S). All patients received flurbiprofen axetil 5 mg/kg