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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Focused ultrasound enhances the anesthetic effects of topical lidocaine in rats

Fig. 3

Data acquisition timeline and derivation of condition-specific SSEP. a Timeline of three sets of experiment sessions. The inverted blue arrowheads indicate the timing of lidocaine application. (US+/-, with/without ultrasound; Lid+/-, with/without lidocaine). ΔTi denotes time-dependent effects of SSEP from the (i + 1)th segment (i = {1, 2, 3}) from each session. b The summary table on the derivation of SSEP features that contain both condition-specific and time-dependent effects within each session. c Group-averaged (n = 10) derivation of condition-specific SSEP (in the right column) by subtracting the SSEP data (e.g., the difference in SSEP segments with respect to the initial segment, ‘US-/Lid-’) of session B/C (middle column) from that of session A (left column). USONLY indicates the effect of ultrasound whereas LidONLY indicates the effect of application of lidocaine. The effect of ultrasound after the application of lidocaine, being isolated from the application of lidocaine alone, is denoted as USIsolated. The dotted black lines indicate the timing of electrical stimulation

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