Development and validation of a predictive score for ICU delirium in critically ill patients

BMC Anesthesiology

Table 1 Characteristics of derivation cohort

Variable	Delirium (n = 46)	No delirium (n = 177)
Age > 65 years, [n(%)]	22(47.8)	61(34.5)
Male/Female, [n(%)]	35/11	110/67
History of hypertension, [n(%)]	24(52.2)	48(27.1)
Heart disease, [n(%)]	10(21.7)	31(17.5)
History of pulmonary dysfunction, [n(%)]	5(10.9)	18(10.2)
Alcohol abuse, [n(%)]	7(15.2)	15(8.5)
History of nicotine, [n(%)]	12(26.1)	29(16.4)
History of peptic ulcer, [n(%)]	2(4.3)	1(0.6)
Hypoxaemia, [n(%)]	28(60.9)	37(20.9)
Hypotension, [n(%)]	27(58.7)	65(36.7)
Deep sedation, [n(%)]	33(71.7)	57(32.2)
Benzodiazepines, [n(%)]	30(65.2)	42(23.7)
Mechanical ventilation, [n(%)]	41(89.1)	74(41.8)
Metabolic acidosis, [n(%)]	17(37.0)	39(22.0)
Sepsis, [n(%)]	29(63)	52(29.4)
Surgery, [n(%)]	23(50)	70(39.5)

(History of pulmonary dysfunction: chronic obstructive pulmonary disease or bronchial asthema before ICU admission; Alcohol abuse: more than 150 ml average daily for ten years; History of nicotine: more than 20 cogaretters average daily for ten years; Hypoxaemia: PaO₂ < 60 mmHg or SpO2 < 90% and successive oxygen therapy or mechanical ventlation more than 24 h after ICU admission; Hypotension:MAP < 65 mmHg and need vascoactive drug support; Deep sedation: a Richmond agitation sedation score (RASS) value of −3 to −5 and using sedatives continuously for more than 3 days after study enrollment; Benzodiazepines: application of Benzodiazepines for 24 h after ICU admission; Metabolic acidosis: PH < 7.35 or Lac> 2.2 mmol/l; Sepsis: met the 2015 sepsis definition of Systemic Inflammatory Response Syndrome)

ISSN: 1471-2253