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Table 2 Biochemical characteristics of survivor and nonsurvivor surgical sepsis patients on day 2 of ICU admission

From: Persistently higher serum sCD40L levels are associated with outcome in septic patients

  Survivor (n = 29) Non-survivor (n = 20) P
Gender (male/female) 22/7 12/8 0.236
Age (years)-median(p25-p75) 56.00 (31.50–64.00) 71.00 (52.25–77.25) 0.023
Septic shock− n (%) 17 (58.6) 10 (50.0) 0.551
Site of infection    0.508
 Respiratory − n (%) 5 (17.2) 5 (25.0)  
 Abdominal − n (%) 24 (82.8) 15 (75.0)  
APACHE II score-median(p25-p75) 12.00 (8.00–16.50) 14.00 (11.25–17.00) 0.156
SOFA score-median(p25-p75) 6.00 (5.00–10.00) 8.50 (6.00–10.00) 0.216
ISTH score-median(p25-p75) 4.00 (2.00–5.00) 3.00 (3.00–4.75) 0.901
JAAM score-median(p25-p75) 4.00 (2.50–5.00) 4.00 (2.50–4.75) 0.835
PT-INR-median(p25-p75) 1.36 (1.25–1.72) 138.5 (128.25–170.75) 0.760
aPTT (seconds)-median(p25-p75) 51.00 (43.60–66.95) 68.65 (53.20–113.95) 0.020
Fibrinogen(g/L)-median(p25-p75) 3.74 (2.55–6.70) 2.83 (1.70–4.78) 0.106
FDP (ug/dl)-median(p25-p75) 16.96 (10.43–33.01) 20.40 (7.37–32.33) 0.823
D-Dimer (ug/ml)-median(p25-p75) 3.96 (2.95–7.61) 3.86 (2.19–7.86) 0.502
Platelet- median*103/mm3 (p25-p75) 109.00 (47.00–191.00) 124.50 (65.25–174.25) 0.903
Leukocytes-median*103/mm3(p25-p75) 13.71 (6.83–17.93) 13.91 (9.06–19.22) 0.376
Lactate (mmol/L)-median (p25-p75) 2.10 (1.30–3.15) 2.75 (1.65–5.60) 0.203
sCD40L(pg/ml)-median (p25-p75) 747.21 (422.46–981.47) 1214.72 (696.28–2089.57) 0.009
Length of stay in the ICU (days)-median (p25-p75) 17.62 (5–20) 12.55 (7–19) 0.341
AKI –n (%) 10/29 (34.48) 6/20 (30.00) 0.749
ARDS-n (%) 12/29 (41.38) 9/20 (45.00) 0.806
PaO2/FiO2 ratio-median(p25-p75) 232.9 (170–300) 236.0 (170–310) 0.900
Subtotal gastrectomy-n(%) 5/29 (17.24) 5/20 (25.00) 0.518
Enteroanastomosis-n(%) 11/29 (37.93) 8/20 (40.00) 0.889
Cholecystectomy-n(%) 5/29 (17.24) 3/20 (15.00) 0.839
Choledocholithotomy-n(%) 8/29 (27.59) 4/20 (20.00) 0.554
  1. p25–75 Percentile 25th–75th, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sepsis-related Organ Failure Assessment, ISTH Thrombosis and Haemostasis, JAAM Japanese Association for Acute Medicine, PT-INR Prothrombin time international normalized ratio, aPTT Activated partial thromboplastin time, FDP Fibrinogen degradation product, AKI Acute kidney injury, ARDS Acute respiratory distress syndrome, PaO2/FiO2 Pressure of arterial oxygen/fraction inspired oxygen