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Table 2 Biochemical characteristics of survivor and nonsurvivor surgical sepsis patients on day 2 of ICU admission

From: Persistently higher serum sCD40L levels are associated with outcome in septic patients

 

Survivor (n = 29)

Non-survivor (n = 20)

P

Gender (male/female)

22/7

12/8

0.236

Age (years)-median(p25-p75)

56.00 (31.50–64.00)

71.00 (52.25–77.25)

0.023

Septic shock− n (%)

17 (58.6)

10 (50.0)

0.551

Site of infection

  

0.508

 Respiratory − n (%)

5 (17.2)

5 (25.0)

 

 Abdominal − n (%)

24 (82.8)

15 (75.0)

 

APACHE II score-median(p25-p75)

12.00 (8.00–16.50)

14.00 (11.25–17.00)

0.156

SOFA score-median(p25-p75)

6.00 (5.00–10.00)

8.50 (6.00–10.00)

0.216

ISTH score-median(p25-p75)

4.00 (2.00–5.00)

3.00 (3.00–4.75)

0.901

JAAM score-median(p25-p75)

4.00 (2.50–5.00)

4.00 (2.50–4.75)

0.835

PT-INR-median(p25-p75)

1.36 (1.25–1.72)

138.5 (128.25–170.75)

0.760

aPTT (seconds)-median(p25-p75)

51.00 (43.60–66.95)

68.65 (53.20–113.95)

0.020

Fibrinogen(g/L)-median(p25-p75)

3.74 (2.55–6.70)

2.83 (1.70–4.78)

0.106

FDP (ug/dl)-median(p25-p75)

16.96 (10.43–33.01)

20.40 (7.37–32.33)

0.823

D-Dimer (ug/ml)-median(p25-p75)

3.96 (2.95–7.61)

3.86 (2.19–7.86)

0.502

Platelet- median*103/mm3 (p25-p75)

109.00 (47.00–191.00)

124.50 (65.25–174.25)

0.903

Leukocytes-median*103/mm3(p25-p75)

13.71 (6.83–17.93)

13.91 (9.06–19.22)

0.376

Lactate (mmol/L)-median (p25-p75)

2.10 (1.30–3.15)

2.75 (1.65–5.60)

0.203

sCD40L(pg/ml)-median (p25-p75)

747.21 (422.46–981.47)

1214.72 (696.28–2089.57)

0.009

Length of stay in the ICU (days)-median (p25-p75)

17.62 (5–20)

12.55 (7–19)

0.341

AKI –n (%)

10/29 (34.48)

6/20 (30.00)

0.749

ARDS-n (%)

12/29 (41.38)

9/20 (45.00)

0.806

PaO2/FiO2 ratio-median(p25-p75)

232.9 (170–300)

236.0 (170–310)

0.900

Subtotal gastrectomy-n(%)

5/29 (17.24)

5/20 (25.00)

0.518

Enteroanastomosis-n(%)

11/29 (37.93)

8/20 (40.00)

0.889

Cholecystectomy-n(%)

5/29 (17.24)

3/20 (15.00)

0.839

Choledocholithotomy-n(%)

8/29 (27.59)

4/20 (20.00)

0.554

  1. p25–75 Percentile 25th–75th, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sepsis-related Organ Failure Assessment, ISTH Thrombosis and Haemostasis, JAAM Japanese Association for Acute Medicine, PT-INR Prothrombin time international normalized ratio, aPTT Activated partial thromboplastin time, FDP Fibrinogen degradation product, AKI Acute kidney injury, ARDS Acute respiratory distress syndrome, PaO2/FiO2 Pressure of arterial oxygen/fraction inspired oxygen