Fig. 3

Syndecan-1 expression of tubular epithelial cells in 12 mmHg and 8 mmHg groups. a, d, g Negative control. b Reduced intensity of proximal tubule syndecan-1 expression in the 12 mmHg group. c Proximal tubule syndecan-1 expression is weaker in the 12 mmHg group than in the 8 mmHg group. e Syndecan-1 expression between the distal tubule of the 12 mmHg group and f the 8 mmHg group was not different. h, i Syndecan-1 expression is negative in the glomerular and peritubular capillaries of both pressure groups. Original magnification was × 400, and red dashed boxes show a higher magnification. Red arrows indicate positive syndecan-1 expression, yellow arrows indicate negative syndecan-1 expression. j The H-score of proximal tubule syndecan-1 expression is lower in the 12 mmHg group than the 8 mmHg group (211.00 (199.05–219.67) vs 225.90 (215.46–231.50), p = 0.030), and is not significantly different between groups in the distal tubules (108.10 (98.49–118.31) vs 112.80 (94.53–128.12), p = 0.8). Data are presented as median (95% CI). The two groups were compared using Mann-Whitney test; * p < 0.05