Table 2 The value of SA and PCT for diagnosing sepsis
From: Usefulness of sialic acid for diagnosis of sepsis in critically ill patients: a retrospective study
Items | Cut-off value | Sensitivity (%) | Specificity (%) | Area under the curve | 95% confidence interval |
|---|---|---|---|---|---|
For diagnosis of sepsis with all pathogen | |||||
SA (mg/L) | 618.1 | 64.2 | 78.3 | 0.763 | 0.715–0.810 |
PCT (ng/ml) | 0.435 | 67.9 | 84.0 | 0.816 | 0.774–0.857 |
Prediction probability value of SA and PCT | 0.335 | 75.2 | 84.6 | 0.854 | 0.816–0.893 |
For diagnosis of sepsis with bacterial infection | |||||
SA (mg/L) | 571.3 | 73.2 | 64.5 | 0.726 | 0.675–0.778 |
PCT (ng/ml) | 0.580 | 66.9 | 83.9 | 0.806 | 0.762–0.851 |
For diagnosis of sepsis with viral infection | |||||
SA (mg/L) | 727.9 | 87.5 | 82.2 | 0.885 | 0.810–0.960 |
PCT (ng/ml) | 1.785 | 62.5 | 80.6 | 0.691 | 0.516–0.865 |
For diagnosis of sepsis with fungal infection | |||||
SA (mg/L) | 692.5 | 0.667 | 77.2 | 0.702 | 0.543–0.861 |
PCT (ng/ml) | 0.055 | 93.3 | 38.0 | 0.654 | 0.537–0.770 |
For diagnosis of sepsis in non-tumor patients | |||||
SA (mg/L) | 571.3 | 75.4% | 70.7% | 0.774 | 0.719–0.828 |
PCT (ng/ml) | 0.58 | 63.1% | 81.8% | 0.771 | 0.718–0.825 |
Prediction probability value of SA and PCT | 0.453 | 72.3% | 85.1% | 0.843 | 0.797–0.890 |