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Table 1 Comparison of characteristics between mild hypercapnia and normocapnia

From: Mild hypercapnia improves brain tissue oxygen tension but not diffusion limitation in asphyxial cardiac arrest: an experimental study in pigs

Variables Hypercapnia (n = 6) Normocapnia (n = 6) P value
Survival for 12 h 6/6 5/6 1
Weight, kg 39.7 ± 1.2 40 ± 0.9 0.835
Duration of asphyxia, minutes 8.1 ± 0.8 8.3 ± 1.1 0.789
Shocks 1 (0, 2) 1 (1, 2) 1
Duration of CPR, minutes 4.4 ± 1.8 5.6 ± 1.2 0.248
Epinephrine, mg 0.8 ± 0.4 0.9 ± 0.6 0.916
Hemoglobin, g/L 149 ± 7 146 ± 8 0.54
Pao2, mmHg
 Baseline 82 ± 12 88 ± 13 0.432
 ROSC 1 h 99 ± 14 107 ± 7 0.221
 ROSC 6 h 83 ± 4 93 ± 8 0.043
 ROSC 12 h 77 ± 4 86 ± 5 0.007
Paco2, mmHg
 Baseline 39 ± 2 40 ± 2 0.958
 ROSC 1 h 52 ± 3 41 ± 2 <  0.001
 ROSC 6 h 51 ± 2 40 ± 1 <  0.001
 ROSC 12 h 50 ± 3 39 ± 2 < 0.001
AJDo2, vol%
 Baseline 6.3 ± 0. 5 6.1 ± 0. 8 0.666
 ROSC 1 h 4.7 ± 1.4 5.7 ± 0.6 0.13
 ROSC 6 h 3.9 ± 0.5 4 ± 0.9 0.91
 ROSC 12 h 4 ± 1.5 4.3 ± 0.6 0.7
LOI, mmol/L/vol%
 Baseline 0.12 ± 0.05 0.11 ± 0.04 0.807
 ROSC 1 h 0.27 ± 0.06 0.21 ± 0.05 0.095
 ROSC 6 h 0.22 ± 0.13 0.27 ± 0.11 0.578
 ROSC 12 h 0.31 ± 0.11 0.3 ± 0.08 0.974
  1. Data were expressed as mean ± SD (standard deviation) or median (interquartile range). Except for the baseline, data of Pao2, Paco2, AJDo2, and LOI after ROSC were calculated from 5 pigs survived for the study period
  2. CPR Cardiopulmonary resuscitation, ROSC Return of spontaneous circulation, Pao2 Pressure of arterial oxygen, Paco2 Pressure of arterial carbon dioxide, AJDo2 Arteriojugular oxygen content difference, LOI Lactate oxygen index