Fig. 2

The knee joints and synovium of dexmedetomidine administrated group. Intact cartilage surfaces without erosion at all time intervals. Mild congestion in dexmedetomidine administrated group at day of 1, 2, 7 and 14. Mild edema at day of 1 and 2. Severe neutrophil infiltration at day of 1 and mild neutrophil infiltration at day of 7. No inflammation was observed in synovium at 14 and 21 days in this group. Single row of synoviocytes surrounding the loose connective tissue was seen. Hematoksilen-eosin, Scale bar: 50 μm