Effects of continuous infusion of phenylephrine vs. norepinephrine on parturients and fetuses under LiDCOrapid monitoring: a randomized, double-blind, placebo-controlled study

Table 3 Maternal outcomes in three groups

Variables	Control group (n = 78)	Phenylephrine group (n = 71)	Norepinephrine group (n = 74)	χ² value	df	P value
Bradycardia (n)	0 (0)	0.03 (2)	0.01 (1)	2.22	2	0.329
Tachycardia (n)	0.10 (8)	0 (0) *	0 (0) ^#	15.43	2	< 0.001
Intraoperative hypotension (n)	0.47 (37)	0.13 (9) *	0.11 (8) ^#	35.31	2	< 0.001
Nausea (n)	0.14 (11)	0.01 (1) *	0.08 (6)	8.07	2	0.018
Vomiting (n)	0.01 (1)	0 (0)	0.01 (1)	0.9	2	0.624
Difficulty breathing (n)	0.12 (9)	0.03 (2)	0.03 (2)	7.12	2	0.028
Dizziness (n)	0.08 (6)	0 (0)	0.03 (2)	6.61	2	0.037

Data expressed as rate (number);*0.25 μg/kg/min phenylephrine vs. control group, P < 0.05; #0.05 μg/kg/min norepinephrine vs. control group, P < 0.05; †0.25 μg/kg/min phenylephrine vs. 0.05 μg/kg/min norepinephrine group, P < 0.05 based on chi-squared test. (after Bonnfini adjust the P value < 0.0167 has the significant different for inter-group comparison)

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