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Table 2 The incidence of intraoperative adverse events and physician interventions

From: A randomised dose-response study of prophylactic Methoxamine infusion for preventing spinal-induced hypotension during Cesarean delivery

 

Group M1

(n = 20)

Group M2

(n = 20)

Group M3

(n = 20)

Group M4

(n = 20)

P value

Hypotension

15 (75%)

11 (55%)

7 (35%)

2 (10%)

< 0.0001

Reactive hypertension

0 (0%)

1 (5%)

2 (10%)

3 (15%)

0.058

Bradycardia

3 (15%)

3 (15%)

3 (15%)

0 (0%)

0.154

Nausea and vomiting

3 (15%)

1 (5%)

1 (5%)

2 (10%)

0.596

Shivering

3 (15%)

0 (0%)

1 (5%)

0 (0%)

0.067

Duration of hypotension for per patient (min)

2.0 ± 1.5

1.2 ± 1.3

0.7 ± 1.0

0.2 ± 0.6

< 0.0001

Number of patients who need rescue methoxamine bolus

14 (70%)

9 (45%)

7 (35%)

2 (10%)

0.0001

Number of patients who need physician interventions

15 (75%)

9 (45%)

9 (45%)

3 (15%)

0.0003

  1. Data are presented as number (%), mean ± SD or median (range); Categorical data were analyzed using the Cochran-Armitage chi-square test for trend
  2. Hypotension: SBP < 80% baseline or < 90 mmHg; Reactive hypertension: SBP > 120% of baseline value. Bradycardia: heart rate < 50 beats/min