| Group M1 (n = 20) | Group M2 (n = 20) | Group M3 (n = 20) | Group M4 (n = 20) | P value |
---|---|---|---|---|---|
Hypotension | 15 (75%) | 11 (55%) | 7 (35%) | 2 (10%) | < 0.0001 |
Reactive hypertension | 0 (0%) | 1 (5%) | 2 (10%) | 3 (15%) | 0.058 |
Bradycardia | 3 (15%) | 3 (15%) | 3 (15%) | 0 (0%) | 0.154 |
Nausea and vomiting | 3 (15%) | 1 (5%) | 1 (5%) | 2 (10%) | 0.596 |
Shivering | 3 (15%) | 0 (0%) | 1 (5%) | 0 (0%) | 0.067 |
Duration of hypotension for per patient (min) | 2.0 ± 1.5 | 1.2 ± 1.3 | 0.7 ± 1.0 | 0.2 ± 0.6 | < 0.0001 |
Number of patients who need rescue methoxamine bolus | 14 (70%) | 9 (45%) | 7 (35%) | 2 (10%) | 0.0001 |
Number of patients who need physician interventions | 15 (75%) | 9 (45%) | 9 (45%) | 3 (15%) | 0.0003 |