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Table 2 Comparisons of effective concentration of rocuronium

From: Effects of hyperthermia on the effective concentration of rocuronium and sugammadex-mediated reversal in isolated phrenic nerve hemidiaphragm preparations of rats

 

36 °C

38 °C

40 °C

P-value among all the groups

36 vs. 38

38 vs. 40

36 vs 40

EC5(μg/)

5.3 (1.3)a

4.2 (1.2)

3.1 (1.0)c

0.0014

0.048

0.066

0.0006

EC10

5.8 (1.2)

4.8 (1.2)

3.7 (1.0)c

0.0014

0.056

0.056

0.0006

EC25

6.5 (1.1)

5.6 (1.1)b

4.5 (0.9)c

0.0015

0.087

0.041

0.0006

EC50

7.2 (1.0)

6.4 (1.1)b

5.3 (0.8)c

0.0014

0.115

0.035

0.0005

EC75

7.9 (0.9)

7.2 (1.0)b

6.2 (0.8)c

0.0014

0.167

0.035

0.0004

EC90

8.6 (0.9)

8.0 (1.0)b

7.0 (0.7)c

0.0011

0.131

0.035

0.0003

EC95

9.1 (0.8)

8.5 (1.0)b

7.6 (0.6)c

0.0015

0.167

0.048

0.0003

  1. Values presented as mean (SD). EC, effective concentration
  2. aP value less than 36 °C vs. 38 °C
  3. bP value less than 38 °C vs. 40 °C
  4. CP value less than 36 °C vs. 40 °C
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BMC Anesthesiology

ISSN: 1471-2253

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