Fig. 5From: The role of NMDA receptors in rat propofol self-administrationThe X-axis represents the dose of MK-801 (mg/kg). The Y-axis represents the total distance covered by rats in 3 h. 0.1 mg/kg or 0.2 mg/kg MK-801 have no changes on general locomotor activity in rats (P > 0.05), whereas the higher 0.4 mg/kg MK-801 dose significantly increased this activity (F (3, 20) = 22.812, P < 0.01Back to article page