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Table 1 Baseline Patient Demographic and Preoperative Characteristics

From: Dexmedetomidine for prevention of postoperative pulmonary complications in patients after oral and maxillofacial surgery with fibular free flap reconstruction:a prospective, double-blind, randomized, placebo-controlled trial

Characteristic Dexmedetomidine group
(n = 80)
Placebo group
(n = 80)
P value
Age, median (IQR), year 59 (55, 65) 62 (56, 67) 0.123
Sex, No. (%)
 Male 51 (63.8) 53 (66.3) 0.740
 Female 29 (36.3) 27 (33.8)  
Hight, median (IQR), cm 168.0 (160.0, 171.5) 166.00 (160.0, 172.0) 0.832
Weight, median (IQR), kg 60.50(55.0, 69.5) 62.00 (57.5, 71.0) 0.284
BMI, median (IQR) a 22.59 (20.36, 24.16) 22.90 (21.03, 25.10) 0.283
ARISCAT score b
 Intermediate risk, No. (%) 77 (96.3) 79 (98.8) 0.311
 High risk, No. (%) 3 (3.8) 1 (1.3)  
 Mean (SD) 28.36 (4.82) 28.32 (4.81)  
ASA physical status classification, No. (%) c
 1 16 (20.0) 17 (21.3) 0.216
 2 61 (76.3) 63(78.7)  
 3 3 (3.8) 0 (0)  
NYHA heart failure class, No. (%) d
 I 47 (58.8) 51 (63.7) 0.516
 II 33 (41.2) 29 (36.2)  
Tobacco use, No. (%) 31 (38.8) 29 (36.2) 0.744
Alcohol use, No. (%) e 25 (31.3) 21 (26.3) 0.485
Preoperative SpO2, No. (%)
  ≥ 96 67 (83.8) 68 (85.0) 0.975
 91–95 12 (15.0) 11 (13.8)  
  ≤ 90 1 (1.3) 1 (1.3)  
Preoperative anemia (Hb ≤ 10 g/dl), No. (%) 9 (11.3) 5 (6.3) 0.263
 Mean (SD), g/dl 13.54 (2.03) 13.72 (1.92)  
Comorbidity
 Arterial hypertension, No. (%) 27 (33.8) 24 (30.0) 0.611
 Diabetes, No. (%) 9 (11.3) 12 (15.0) 0.483
 Coronary artery disease, No. (%) 8 (10.0) 4 (5.0) 0.230
 Arrhythmia, No. (%) 6 (7.5) 6 (7.5) 1.000
 COPD, No. (%) 1 (1.3) 4 (5.0) 0.173
 Asthma, No. (%) 0 (0.0) 1 (1.3) 0.316
Preoperative abnormalities on chest radiography, No. (%) 4 (5.0) 8 (10.0) 0.230
Active cancer, No. (%) 69 (86.3) 70 (87.5) 0.815
  1. Abbreviations: IQR Interquartile range, BMI Body mass index, ARISCAT Assess Respiratory Risk in Surgical Patients in Catalonia, ASA American Society of Anesthesiology, NYHA New York Heart Association, SpO2 Oxygen saturation as measured by pulse oximetry, Hb Hemoglobin, COPD Chronic obstructive pulmonary disease
  2. a Calculated as weight in kilograms divided by height in meters squared
  3. b Score range is from 0 to 123; higher scores indicate a higher risk of postoperative pulmonary complications. Patients with scores of 26 to 44 are considered at intermediate risk; those with scores more than 44 are considered at high risk
  4. c Score range is from 1 to 6 and includes a classification for normal health as 1; mild systemic disease, 2; severe systemic disease, 3; severe systemic disease that is a constant threat to life,4. patients with scores of 5 or 6 were excluded
  5. d Score range is from I to IV; higher scores indicate a higher extent of heart failure. Patients without limitation of their ordinary physical activity are classified NYHA class I; those with slight limitation of their activity are classified as NYHA class II. Patients with scores of III or IV were excluded
  6. e Defined as more than 2 drinks per day during the past 2 weeks