Table 1 Patient characteristics
From: Predictive factors for successful INTELLiVENT-ASV® use: a retrospective observational study
All patients | I-ASV success | I-ASV failure | P-value | |
|---|---|---|---|---|
(n = 189) | (n = 135) | (n = 54) | ||
Age, years | 65 (52–74) | 65 (50–74) | 65 (54–74) | 0.555 |
Sex, male | 52.9% | 50.4% | 59.3% | 0.333 |
Height, cm | 160 (153–167) | 159 (153–165) | 162 (153–169) | 0.160 |
Weight, kg | 58 (50–67) | 58 (51–67) | 59 (50–68) | 0.448 |
BMI, kg/m2 | 22.6 (20.7–25.8) | 22.6 (20.8–25.3) | 22.5 (19.9–27.3) | 0.798 |
APACHE II | 23 (17–27) | 21 (15–26) | 26 (21–34) | <.0001 |
Presence of sepsis | 52.9% | 48.9% | 61.1% | 0.148 |
CKD on HD | 6.9% | 5.9% | 9.3% | 0.525 |
CRRT | 20.1% | 10.4% | 44.4% | <.0001 |
SOFA (day1) | 9 (6–12) | 8 (6–11) | 11 (8–15) | <.0001 |
Use of vasopressors (day1) | 57.7% | 52.6% (71) | 70.4% (38) | 0.034 |
Reasons for admission | <.0001 | |||
Elective surgery | 94.1% (32) | 5.9% (2) | ||
Emergent surgery | 81.5% (53) | 18.5% (12) | ||
Medical reasons | 55.6% (50) | 44.4% (40) | ||
Sedatives and analgesics | ||||
Fentanyl | 100% | 100% | – | |
Morphine | 5.2% | 27.8% | <.0001 | |
Neuromuscular blockade | 4.4% | 25.9% | <.0001 | |
Reasons for ventilation | <.0001 | |||
Respiratory failure | 15.6% (21) | 50.0% (27) | ||
Hemodynamic instability | 8.9% (12) | 13.0% (7) | ||
Central nervous dysfunction | 11.1% (15) | 7.4% (4) | ||
Sepsis | 33.3% (45) | 16.7% (9) | ||
Highly invasive surgery | 11.9% (16) | 1.9% (1) | ||
Flap surgery | 9.6% (13) | 0% (0) | ||
Post resuscitation | 3.0% (4) | 3.7% (2) | ||
Trauma | 3.0% (4) | 3.7% (2) | ||
Other | 3.7% (5) | 3.7% (2) | ||
P/F ratio | 252 (174–334) | 278 (206–366) | 167 (98–246) | 0.0003 |
P/F ratio classification | <.0001 | |||
≥ 300 | 89.4% (84) | 10.6% (10) | ||
≤ 200 to < 300 | 71.4% (25) | 28.6% (10) | ||
≤ 100 to < 200 | 47.5% (19) | 52.5% (21) | ||
< 100 | 35.0% (7) | 65.0% (13) | ||
MV duration, days | 6 (4–10) | 5 (3–8) | 10 (7–16) | <.0001 |
MV after ICU | 13.2% | 9.6% | 22.2% | 0.031 |
ICU mortality | 4.8% | 1.5% | 13.0% | 0.003 |
ICU duration, days | 7 (5–11) | 6 (4–9) | 11 (8–16) | <.0001 |