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Table 3 LSD multiple comparison tests of the main results at LOC induced by propofol

From: The effects of different doses of dexmedetomidine on the requirements for propofol for loss of consciousness in patients monitored via the bispectral index: a double-blind, placebo-controlled trial

 

Propofol requirements (mg·kg− 1)

BIS values

Time to LOC (s)

Difference (95% CI) P

Difference (95% CI) P

Difference (95% CI) P

Control group vs. 0.5 μg· kg− 1DEX group

0.68 (0.49 to 0.87) 0.0001

−7.04 (− 9.23 to − 4.85) 0.0001

99.91 (76.20 to 123.63) 0.0001

Control group vs. 1.0 μg·kg− 1DEX group

1.02 (0.84 to 1.21) 0.0001

−7.58 (−9.75 to −5.41) 0.0001

177.56 (154.08 to 201.03) 0.0001

0.5 μg·kg− 1DEX group vs. 1.0 μg·kg− 1DEX group

0.34 (0.16 to 0.54) 0.0001

−0.54 (− 2.71 to1.63) 0.621

77.64 (54.17 to 101.12) 0.0001

  1. Statistical significance was defined as P < 0.05