Skip to main content

Table 1 Characteristics of studies included in Meta-analysis

From: The efficacy of Antipyretic Analgesics administration intravenously for Preventing Rocuronium-Associated Pain/Withdrawal Response: a systematic review and meta-analysis

Study

Country

Surgical setting

Age

(yr)

ASA

Administration

method

Group

(n, patients)

Outcomes

Younghoon Jeon 2010

Korea

Elective

surgery

45.4 ± 11.1

45.9 ± 14.2

50.1 ± 10.6

I-II

IVVO

N S (n = 39)

lidocaine 40 mg (n = 39)

paracetamol 50 mg (n = 40)

A/B/C/D

Yonghong Zhang 2012

China

Elective

surgery

45.18 ± 12.44

41.28 ± 14.12

45.24 ± 14.36

43.54 ± 15.01

I-II

IVVO

N S (n = 40)

lidocaine 40 mg(n = 40)

parecoxib 20 mg(n = 40)

parecoxib 40 mg(n = 40)

A/B/C/D

Younghoon Jeon 2013

Korea

Elective

surgery

46.8 ± 11.5

48.5 ± 13.1

46.2 ± 16.3

I-II

IVVO

placebo(n = 35)

lidocaine 20 mg(n = 35)

ketorolac 10 mg(n = 35)

A/B/C/D

Gülnaz Ateş 2014

Turkey

Elective

surgery

36.45 ± 12.94

35.58 ± 11.9

39.27 ± 11.81

I-II

IVVO

N S (n = 60)

lidocaine 40 mg(n = 60)

paracetamol 50 mg(n = 60)

A/B/C/D

Sennur Uzun 2014

Turkey

3 kinds of elective

surgeries

41.8 ± 13.9

42.7 ± 11.9

41.7 ± 13.3

I-II

IVVO

N S(n = 50)

lidocaine 40 mg(n = 50)

aracetamol 50 mg(n = 50)

A/B/C/D

Cheng Yuan 2014

China

Elective surgery

45.8 ± 10.3

46.9 ± 9.6

44.3 ± 9.8

43.7 ± 10.6

I-II

IV

IVVO

IV

IVVO

N S (n = 20)

N S (n = 20)

flurbiprofen 50 mg(n = 20)

flurbiprofen 50 mg(n = 20)

A/B/D

Li Sha 2014

China

Elective

surgery

46.7 ± 11.1

48.4 ± 13.2

46.2 ± 14.6

I-II

IVVO

N S (n = 35)

lidocaine 40 mg (n = 35)

flurbiprofen 50 mg(n = 35)

A/B/C/D

Ma Qingjie

2016

China

Elective

surgery

39.2 ± 3.7

38.5 ± 4.1

40.3 ± 5.2

I

IV

N S (n = 40)

parecoxib20mg (n = 40)

parecoxib40mg (n = 40)

A/B

Yu Liang 2018

China

Elective

surgery

40.7 ± 8.7

42.7 ± 7.7

43.7 ± 7.3

I-II

IV

N S (n = 20)

lornoxicam 4 mg(n = 20)

lornoxicam 8 mg(n = 20)

A/B

  1. NS normal saline, A the incidence of rocuronium-associated injection pain/withdrawal response, B the incidence of different severities rocuronium-associated injection pain/withdrawal response, C occurrence of injection pain caused by antipyretic analgesics (AAs and lidocaine), D local reaction of injection site, IVVO injection intravenously with venous occlusion, IV intravenous directedly