Variables | Number of studies involved (total number of patients) | Intervention group | Standard therapy group | RR (95% CI) |
---|---|---|---|---|
Intraoperative period | ||||
Use of vasoactive drugs | 15 (N = 4104) | N = 785 (19.1%) | N = 609 (14.8%) | 1.24 (1.13–1.37) |
Crystalloid fluids (mL); median (min-max) | 17 (N = 2681) | 3000 (1000–6713) | 2558 (1286–6200) | |
Colloid fluids (mL); median (min-max) | 18 (N = 4393) | 1188 (0–2426) | 817 (0–2236) | |
Blood products (mL); median (min-max) | 15 (N = 4420) | 244.5 (0–825) | 267 (0–975) | |
Complications (postoperative period) | 21 (N = 4872) | 1017 (20.9%) | 1350 (27.7%) | 0.75 (0.70–0.81) |
Infectious complications | 17 (N = 4530) | N = 384 (8.4%) | N = 581 (12.8%) | 0.66 (0.58–0.74) |
Respiratory complications | 19 (N = 4655) | N = 160 (3.4%) | N = 193 (4.1%) | 0.82 (0.67–1.02) |
Renal complications | 19 (N = 4655) | N = 108 (2.3%) | N = 158 (3.4%) | 0.68 (0.54–0.87) |
Cardiovascular complications | 21 (N = 4872) | N = 365 (7.4%) | N = 418 (8.5%) | 0.87 (0.76–0.99) |
Length of ICU stay (days); median (min-max) | 14 (N = 1637) | 1.9 (0–5) | 2.9 (0–5) | |
Mortality rate | 20 (N = 4712) | N = 125 (2.6%) | N = 122 (2.5%) | 1.02 (0.80–1.31) |
Length of hospital stay (days); median (min-max) | 20 (N = 4852) | 10 (5–20) | 11 (6–20) |