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Table 1 Demographics, biometrics, pre and postoperative liver and renal function data. Values are expressed as the mean ± SD unless otherwise indicated. Postoperative data refers to laboratory tests conducted when the patient was admitted into the ICU after LTx.

From: SUGAMMADEX versus neostigmine after ROCURONIUM continuous infusion in patients undergoing liver transplantation

 

Sugammadex n = 21

Neostigmine n = 20

 

Gender

female, n and (%)

7 (33)

8 (40)

 

male, n and (%)

14 (67)

12 (60)

 

Age (years)

54.1 ± 9.8

54.1 ± 10.4

 

Weight (kg)

73.9 ± 14.2

73.1 ± 14.7

 

Height (m)

1.7 ± 0.1

1.7 ± 0.1

 

BMI (kg/m2)

25.2 ± 4.2

25.3 ± 3.9

 

Liver disease:

HBV-related cirrhosis ± HCC, n and (%)

2 (9.5)

0 (0)

 

HCV-related cirrhosis ± HCC, n and (%)

9 (42.8)

6 (30)

 

Alcohol-related cirrhosis ± HCC, n and (%)

6 (28.5)

6 (30)

 

Alchohol + HBV-related cirrhosis, n and (%)

1 (4.7)

0 (0)

 

Alchohol + HCV-related cirrhosis, n and (%)

0 (0)

4 (20)

 

HIV coexists, n and (%)

2 (9.5)

2 (9.5)

 

Other disease, n and (%)

3 (14.2)

4 (19)

 

Pre-operative liver and renal function

  

p

MELD

16.8 ± 7.3

21.4 ± 9.1

0.1

AST (IU/l)

67.4 ± 39.1

122.8 ± 62

0.15

ALT (IU/l)

48.6 ± 41.1

89.7 ± 168.7

0.30

LDH pre-op (IU/l)

485.3 ± 191.5

457.8 ± 368.4

0.93

TBil (mg/dl)

6.7 ± 10.2

11.5 ± 13.4

0.45

DBil (mg/dl)

3.8 ± 6.1

6.1 ± 8.2

0.6

GGT (IU/l)

155 ± 340

75 ± 74

0.34

Albumin (mg/dl)

29.9 ± 6.2

31 ± 6.4

0.27

ClCr (ml/min)

86.5 ± 34.9

80.7 ± 36.8

0.61

Postoperative liver and renal function

AST (IU/ml)

1246 ± 1060

1688 ± 1508

0.29

ALT (IU/m)

654 ± 348

1346 ± 1594

0.07

LDH (IU/l)

2986 ± 1699

3957 ± 5804

0.49

TBil (mg/dl)

4.6 ± 2.5

6.9 ± 4.6

0.25

DBil (mg/dl)

3.2 ± 2

4 ± 3.2

0.65

GGT (IU/l)

58 ± 47

77 ± 56

0.27

Albumin (mg/dl)

19.8 ± 8

21.3 ± 6

0.82

ClCr (ml/min)

86.2 ± 30.7

72.2 ± 29.1

0.14

  1. Abbreviations: BMI body mass index; MELD Model for End-Stage Liver Disease; AST aspartate aminotransferase; ALT alanine aminotransferase; LDH lactate dehydrogenase; TBil total bilirubin; DBil direct bilirubin; GGT gamma glutamyl-transferase; ClCr estimated creatinine clearance (Cockroft-Gault formula used)