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Table 1 Characteristics of included randomized controlled studies

From: The analgesic efficacy compared ultrasound-guided continuous transverse abdominis plane block with epidural analgesia following abdominal surgery: a systematic review and meta-analysis of randomized controlled trials

Author /Year

Group(n)

Types of surgery

Surgical approach

TAP block technique

Catheter site

Local anesthetic administered for TAP block

Local anesthetic administered for Epidural analgesia

Anesthetic strategy

Additional NSAIDs drugs for TAP block

Postoperative opioid analgesia required

Kadam 2013 [23]

TAP group(22) EA group(19)

Colorectal Upper gastrointestinal Urological

laparotomy

US-guided, single injection followed by continuous infusion

Bilateral Posterior

0.375% ropivacaine 20 ml single-injection bilaterally, followed by 0.2% ropivacaine at 8 mL/h through each catheter for 72 h

0.2% ropivacaine(8-15 ml) bolus followed by 0.2% ropivacaine at 5–15 ml/h

GA

paracetamol 1.0 g every 8 h

PCA using fentanyl 10 to 40 μg bolus per press with a lockout time of 6 min and no basal infusion

Niraj 2011 [22]

TAP group(27) EA group(31)

Partial hepatectomy

Pancreatic surgery

Radical nephrectomy

Biliary bypass

laparotomy

US-guided, single injection followed by continuous infusion

Bilateral Subcostal

0.375% bupivacaine (1 mg/kg) single-injection bilaterally, followed a bolus of 0.375% bupivacaine(1 mg/kg) very 8 h through each catheter for 72 h

0.25% bupivacaine(20 ml) followed by 0.125% bupivacaine with 2 μg/ml Fentanyl at 6-12 mL/h for 72 h (2 ml bolus, lockout 30mins)

GA

paracetamol 1 g every 6 h

intravenous tramadol as required

Niraj 2014 [13]

TAP group(30) EA group(31)

Right hemicolectomy

Left hemicolectomy

Anterior resection

Sigmoid colectomy

Ileocolic resection

laparoscope

US-guided, single injection followed by continuous infusion

Bilateral Posterior

0.375% levobupivacaine (1.25 mg/kg)single-injection bilaterally,followed by 0.25% levobupivacaine at 8–10 mL/h through both catheters for 72 h

0.25% Bupivacaine 20 mL followed by 0.125% bupivacaine with 2 μg/mL fentanyl at 8–12 mL/h (2 ml bolus, lockout 30mins)

GA

paracetamol 1 g every 6 h, diclofenac 150 mg/day

intravenous tramadol as required

Ganapathy 2015 [25]

TAP group(26) EA group(24)

Small bowel surgery

Large bowel surgery

Ostomy reversal

Whipples’operation

laparotomy

US-guided, single injection followed by continuous infusion

Bilateral Subcostal Inferior

0.2% ropivacaine 30 ml single-injection bilaterally followed by 0.35% ropivacaineat 4–5 ml/h for 72 h

0.25% bupivacaine 5 ml followed by 0.1% bupivacaine with hydromorphone(10 mg/mL) at 8 ml/h for 72 h

GA

naproxen 500 mg twice daily, paracetamol 650 mg every 6 h

PCA using hydromorphone 0.2 mg bolus per press with a lockout time of 6 min and no basal infusion

Lyer 2017 [27]

TAP group(33) EA group(36)

lower abdominal surgery

laparotomy

US-guided, single injection followed by continuous infusion

Bilateral Posterior

0.125% bupivacaine 20 ml single-injection bilaterally followed by 15 ml bolus every 8 h through each catheter for 48 h

0.125% bupivacaine 10 ml followed by 0.125% bupivacaine 10 ml every 8 h for 48 h

GA

Paracetamol 1 g was given to patients if their VAS scores were > 3/10

intravenous tramadol as required

Qin 2016 [26]

TAP group(35) EA group(36)

laparoscopic colorectal surgery

laparoscope

US-guided, single injection followed by continuous infusion

Bilateral Posterior

0.375% ropivacaine 1.25 mg/kg single-injection bilaterally followed by 0.2% ropivacaine at 6–8 ml/h through both catheters for 48 h

0.375% ropivacaine 10 ml followed by 0.15% ropivacaine with fentanyl 2 μg/ml at 3–6 mL/h for 48 h (3 ml bolus, lockout 15mins)

GA

/

Intravenous tramadol as required

Wahba 2014 [24]

TAP group(22) EA group(22)

Large bowel surgery Small bowel surgery Gastrectomy Abdominal Hernia

laparotomy

US-guided, single injection followed by continuous infusion

Bilateral Subcostal

0.25% bupivacaine 20 ml single-injection bilaterally followed by 15 ml bolus every 8 h through each catheter for 48 h

0.125% bupivacaine 10 ml followed by 0.125% bupivacaine at 6–8 ml/h for 48 h

GA

/

PCA 1 mg morphine bolus per press with a lockout interval of 10 min

Dai 2017 [15]

TAP group(27) EA group(30)

laparoscopic colorectal surgery

laparoscope

US-guided, single injection followed by continuous infusion

Bilateral Posterior

0.375% ropivacaine 0.15 ml/kg single-injection bilaterally followed by 0.2% ropivacaine at 0.1 ml/kg/h through both catheters for 48 h

0.375% ropivacaine 8-10 ml followed by 0.15% ropivacaine at a 3–4 ml/h for 48 h (3 ml bolus, lockout 15mins)

GA

/

intravenous tramadol as required

  1. IV intravenous, PCA patient controlled analgesia, TAP transverse abdominis plane, US ultrasound, GA General anesthesia