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Table 4 Subgroup analysis for 90-day mortality according to dosage of neostigmine and sugammadex

From: Association of neuromuscular reversal by sugammadex and neostigmine with 90-day mortality after non-cardiac surgery

Variable

Multivariable Cox regression model

P-value

Hazard ratio (95% CI)

Neostigmine dosage, mcg kg− 1 (n = 61,124)

 Q1 < 27.5 (n = 15,108)

1

 

 27.5 ≤ Q2 < 31.8 (n = 15,464)

0.75 (0.53, 1.06)

0.102

 31.8 ≤ Q3 < 36.4 (n = 15,582)

0.89 (0.63, 1.25)

0.491

 36.4 ≤ Q4 (n = 14,970)

0.96 (0.66, 1.42)

0.853

Sugammadex dosage, mg kg−1 (n = 4578)

 Q1 < 2.8 (n = 1214)

1

 

 2.8 ≤ Q2 < 3.1 (n = 963)

0.94 (0.11, 7.78)

0.955

 3.1 ≤ Q3 < 3.6 (n = 1278)

2.27 (0.34, 15.15)

0.397

 3.6 ≤ Q4 (n = 1123)

2.91 (0.30, 27.91)

0.354

  1. All covariates were included in the multivariable model
  2. CI confidence interval